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DSE

Official Full Name

dermatan sulfate epimerase
Overview

The protein encoded by this gene is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. This gene product is localized to the endoplasmic reticulum. Two transcript variants encoding the same protein have been found for this gene.
Synonyms

DSE; dermatan sulfate epimerase; SART2, squamous cell carcinoma antigen recognized by T cells 2; dermatan-sulfate epimerase; DSEPI; Chondroitin glucuronate 5 epimerase; DS epimerase; OTTHUMP00000040406; SART 2; Squamous cell carcinoma antigen recognized by T cells 2; OTTHUMP00000017059; chondroitin-glucuronate 5-epimerase; squamous cell carcinoma antigen recognized by T-cells 2; DSEP; SART2; SART-2;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Zebrafish

Source

E.coli
HEK293
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
N/A
N

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	DSE-2888H	Recombinant Human DSE Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	DSE-511HCL	Recombinant Human DSE cell lysate		N/A		Inquiry
Human	DSE-1387H	Recombinant Human DSE Protein, His-tagged	E.coli	N-His	Tyr23-His284	Inquiry
Human	DSE-4253HF	Recombinant Full Length Human DSE Protein, GST-tagged	In Vitro Cell Free System	GST	958 amino acids	Inquiry
Mouse	DSE-4837M	Recombinant Mouse DSE Protein	Mammalian Cell	His		Inquiry
Mouse	DSE-2536M	Recombinant Mouse DSE Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	DSE-2536M-B	Recombinant Mouse DSE Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	DSE-3319Z	Recombinant Zebrafish DSE	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
DSE Related Articles

DSE involved in several pathways and played different roles in them. We selected most pathways DSE participated on our site, such as Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with DSE were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	CHPF2;CHST3;B3GALT6;CHSY1;CSGALNACT1;XYLT2;CHST3B;CHPF;B3GAT3
Metabolic pathways	ATP5G1;AANAT;CYP2P8;NDUFC2;HOGA1;MOCS1;GPT2L;NT5C3B;ACY1

DSE has several biochemical functions, for example, chondroitin-glucuronate 5-epimerase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by DSE itself. We selected most functions DSE had, and list some proteins which have the same functions with DSE. You can find most of the proteins on our site.

Function	Related Protein
chondroitin-glucuronate 5-epimerase activity	DSEL;DSE

DSE has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DSE here. Most of them are supplied by our site. Hope this information will be useful for your research of DSE.

ACSL4; CPSF3L

Jenvey, CJ; Reichel, MP; et al. Investigation of the comparative sensitivity of serum, colostrum and whey for the detection of specific antibodies in sheep vaccinated against Johne's disease. SMALL RUMINANT RESEARCH 123:193-195(2015).

Marciniuk, K; Maattanen, P; et al. Development of a Multivalent, PrPsc-Specific Prion Vaccine through Rational Optimization of Three Disease-Specific Epitopes. VACCINE 32:1988-1997(2014).