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ECH1

  • Official Full Name

    enoyl CoA hydratase 1, peroxisomal

  • Overview

    This gene encodes a member of the hydratase/isomerase superfamily. The gene product shows high sequence similarity to enoyl-coenzyme A (CoA) hydratases of several species, particularly within a conserved domain characteristic of these proteins. The encoded protein, which contains a C-terminal peroxisomal targeting sequence, localizes to the peroxisome. The rat ortholog, which localizes to the matrix of both the peroxisome and mitochondria, can isomerize 3-trans,5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA, indicating that it is a delta3,5-delta2,4-dienoyl-CoA isomerase. This enzyme functions in the auxiliary step of the fatty acid beta-oxidation pathway. Expression of the rat gene is induced by peroxisome proliferators.
  • Synonyms

    ECH1; enoyl CoA hydratase 1, peroxisomal; enoyl Coenzyme A hydratase 1, peroxisomal; delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial; HPXEL; dienoyl-CoA isomerase; peroxisomal enoyl-CoA hydratase 1; delta3,5-delta2,4-dienoyl-CoA isomerase;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ECH1-12267H Recombinant Human ECH1, GST-tagged E.coli GST 1-328a.a.
Human ECH1-2812H Recombinant Human Enoyl CoA Hydratase 1, Peroxisomal, His-tagged E.coli His
Human ECH1-3030H Recombinant Human ECH1 Protein, GST-tagged Wheat Germ GST
Human ECH1-486H Recombinant Human ECH1, His tagged E.coli His
Human ECH1-28224TH Recombinant Human ECH1, His-tagged E.coli His 295 amino acids
Human ECH1-6730HCL Recombinant Human ECH1 293 Cell Lysate HEK293 N/A
Human ECH1-2849H Recombinant Human ECH1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human ECH1-2023H Recombinant Human ECH1 Protein (Met1-Leu328), N-His tagged E.coli N-His Met1-Leu328
Human ECH1-4161HF Recombinant Full Length Human ECH1 Protein, GST-tagged In Vitro Cell Free System GST 328 amino acids
Mouse ECH1-4965M Recombinant Mouse ECH1 Protein Mammalian Cell His
Mouse Ech1-2716M Recombinant Mouse Ech1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse ECH1-2621M Recombinant Mouse ECH1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse ECH1-2621M-B Recombinant Mouse ECH1 Protein Pre-coupled Magnetic Beads HEK293
Rat ECH1-2001R Recombinant Rat ECH1 Protein Mammalian Cell His
Rat ECH1-1658R Recombinant Rat ECH1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat ECH1-1658R-B Recombinant Rat ECH1 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish ECH1-1577Z Recombinant Zebrafish ECH1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

ECH1 involved in several pathways and played different roles in them. We selected most pathways ECH1 participated on our site, such as Fatty Acid Biosynthesis, Peroxisome, which may be useful for your reference. Also, other proteins which involved in the same pathway with ECH1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Fatty Acid BiosynthesisECHDC3;ACACB;FASN;ACSL5;ECHDC2;ACSL3A;ACSBG1;ECH1;OLAH
PeroxisomeXDH;PXMP2;HMGCLL1;ABCD4;ECI2;ACAA1A;PEX12;FAR1;HAO1

ECH1 has several biochemical functions, for example, isomerase activity, protein binding, receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ECH1 itself. We selected most functions ECH1 had, and list some proteins which have the same functions with ECH1. You can find most of the proteins on our site.

Function Related Protein
isomerase activityPTGESL;TOP1L;ITPK1A;GPIA;PPIFB;FKBP1AB;PGAM1;GPR19;TSTA3
protein bindingGABARAPL1;CD160;PLEKHM1;BEX2;CCDC59;STAU1;DYNLL1;TTC12;GIMAP5
receptor bindingCD276;NRG2B;PLAUR;LAMA1;HSPA1A;PTK6B;PSPN;F2;ANGPTL2

ECH1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ECH1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ECH1.

TRAF1; FAM9B; EEF1G; STAT3; HTT; MCC; TIMP1; EEF1D; CSTF2; SERPINB9; PEX5; PAFAH1B3; purL

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