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EDC3

  • Official Full Name

    enhancer of mRNA decapping 3 homolog (S. cerevisiae)

  • Overview

    EDC3 is associated with an mRNA-decapping complex required for removal of the 5-prime cap from mRNA prior to its;degradation from the 5-prime end (Fenger-Gron et al., 2005 (PubMed 16364915)).
  • Synonyms

    EDC3; enhancer of mRNA decapping 3 homolog (S. cerevisiae); LSM16, LSM16 homolog (EDC3, S. cerevisiae) , YJDC, yjeF domain containing (E.coli); enhancer of mRNA-decapping protein 3; FLJ21128; hYjeF_N2 15q23; YJEFN2; EDC 3; Enhancer of mRNA decapping 3 homolog; Enhancer of mRNA decapping protein 3; FLJ31777; LSM 16; LSM16; LSM16 homolog (EDC3 S. cerevisiae); LSM16 homolog; YJDC; YjeF domain containing; YjeF domain containing protein 1; yjeF_N2; hYjeF_N2; hYjeF_N2-15q23; OTTHUMP00000183472; yjeF domain-containing protein 1; LSM16 homolog (EDC3, S. cerevisiae); yjeF N-terminal domain-containing protein 2;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human EDC3-12276H Recombinant Human EDC3, GST-tagged E.coli GST 158-508a.a.
Human EDC3-6726HCL Recombinant Human EDC3 293 Cell Lysate HEK293 N/A
Human EDC3-4267H Recombinant Human EDC3 Protein, GST-tagged Wheat Germ GST
Human EDC3-801H-B Recombinant Human EDC3 Protein Pre-coupled Magnetic Beads HEK293
Human EDC3-6554H Recombinant Human EDC3 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human EDC3-3501H Recombinant Human EDC3 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human EDC3-4908HF Recombinant Full Length Human EDC3 Protein, GST-tagged In Vitro Cell Free System GST 508 amino acids
Human EDC3-801H Recombinant Human EDC3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human EDC3-533HFL Recombinant Full Length Human EDC3 Protein, C-Flag-tagged Mammalian cells Flag
Mouse Edc3-2725M Recombinant Mouse Edc3 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rhesus Macaque EDC3-1374R Recombinant Rhesus monkey EDC3 Protein, His-tagged Mammalian Cell His
Rhesus Macaque EDC3-1199R Recombinant Rhesus Macaque EDC3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque EDC3-1199R-B Recombinant Rhesus Macaque EDC3 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish EDC3-2641Z Recombinant Zebrafish EDC3 Mammalian Cell His
Chicken EDC3-2245C Recombinant Chicken EDC3 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • EDC3 Related Articles

EDC3 involved in several pathways and played different roles in them. We selected most pathways EDC3 participated on our site, such as RNA degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with EDC3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
RNA degradationLSM8;ENO3;PABPC1A;TOB1B;ZCCHC7;ENO1;PABPC1L;EDC4;SKIV2L2

EDC3 has several biochemical functions, for example, identical protein binding, mRNA binding, phosphodiesterase decapping endonuclease activity. Some of the functions are cooperated with other proteins, some of the functions could acted by EDC3 itself. We selected most functions EDC3 had, and list some proteins which have the same functions with EDC3. You can find most of the proteins on our site.

Function Related Protein
identical protein bindingSID4;IK;HOOK1;RAD51;CEP57L1;CLDN6;ATL1;SIRT1;GRIK5
mRNA bindingADARB1;NANOS2;MRPL13;SRSF1;DCP1B;RPS13;RBPMS2B;LIN28A;FYTTD1
phosphodiesterase decapping endonuclease activity
protein bindingGM5506;Serpina1b;SPC25;TMEM93;LCE3C;GTF2H3;LACTB2;RAD18;RPL22

EDC3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EDC3 here. Most of them are supplied by our site. Hope this information will be useful for your research of EDC3.

DCP1B; DCP1A; DDX6; YWHAB

Kim, EC; Kim, J; et al. Deletion analysis of LSm, FDF, and YjeF domains of Candida albicans Edc3 in hyphal growth and oxidative-stress response. JOURNAL OF MICROBIOLOGY 53:111-115(2015).
Jung, JH; Kim, J; et al. Roles of Edc3 in the oxidative stress response and CaMCA1-encoded metacaspase expression in Candida albicans. FEBS JOURNAL 281:4841-4851(2014).
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