EEA1
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Official Full Name
early endosome antigen 1
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Overview
Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in endosomal trafficking. -
Synonyms
EEA1; early endosome antigen 1; MST105; ZFYVE2; MSTP105; early endosome antigen 1, 162kD; endosome-associated protein p162; early endosome-associated protein; zinc finger FYVE domain-containing protein 2;
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- E.coli
- HEK293
- HEK293T
- Mamanlian cells
- Mammalian Cell
- Wheat Germ
- Flag
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- Myc|DDK
- N/A
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
---|---|---|---|---|---|---|
Human | EEA1-26H | Recombinant Human EEA1 protein, MYC/DDK-tagged | HEK293 | Myc/DDK | ||
Human | EEA1-28464TH | Recombinant Human EEA1 | Wheat Germ | N/A | 100 amino acids | |
Human | EEA1-3902H | Recombinant Human EEA1 protein, His-tagged | E.coli | His | His1232~Lys1348 | |
Human | EEA1-9389HFL | Recombinant Full Length Human EEA1 protein, Flag-tagged | Mamanlian cells | Flag | ||
Human | EEA1-301519H | Recombinant Human EEA1 protein, GST-tagged | E.coli | GST | Lys1151-Ala1350 | |
Mouse | EEA1-4996M | Recombinant Mouse EEA1 Protein | Mammalian Cell | His | ||
Mouse | Eea1-2731M | Recombinant Mouse Eea1 Protein, Myc/DDK-tagged | HEK293T | Myc/DDK | ||
Mouse | EEA1-2643M | Recombinant Mouse EEA1 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Mouse | EEA1-2643M-B | Recombinant Mouse EEA1 Protein Pre-coupled Magnetic Beads | HEK293 |
- Involved Pathway
- Protein Function
- Interacting Protein
- EEA1 Related Articles
- EEA1 Related Research Area
EEA1 involved in several pathways and played different roles in them. We selected most pathways EEA1 participated on our site, such as Endocytosis, Phagosome, Tuberculosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with EEA1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
---|---|
Endocytosis | CLTCB;SMURF2;RHOAD;TSG101;ADRBK2;GIT2B;STAMBPB;LDLRAP1B;CXCR2 |
Phagosome | TUBA8;H2-AB1;DYNC1LI1;C1RA;HGS;CD14;CTSSB.2;ABCB3L1;HLA-DPA1 |
Tuberculosis | TGFB3;HLA-DRB5;IFNA2;BAD;SRC;IL10RB;IFNA14;RAF1;KSR1 |
EEA1 has several biochemical functions, for example, 1-phosphatidylinositol binding, GTP-dependent protein binding, calmodulin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EEA1 itself. We selected most functions EEA1 had, and list some proteins which have the same functions with EEA1. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
1-phosphatidylinositol binding | PICALM;ZFYVE9;MCF2L;PLEKHA2;SCARB1;SNAP91;WDFY3;SNX9;SCIN |
GTP-dependent protein binding | AP3B1;RASGRP4;RAB5B;MRAS;PPIAL4A;PARD6A;RAPGEF5;CDC42;HPS6 |
calmodulin binding | NOS2;KCNQ1;RGS16;EPB41B;ORAI1;MYO6;MYH9;PHKG2;REM1 |
protein binding | PTPN11A;PKHD1L1;CUL3;TBCEL;RFC4;UHMK1;LAMP1;KRAS;ODC1 |
protein homodimerization activity | ADRB3;SLC14A2;CAV2;NR6A1;IKZF3;TERF2;HSP90AA1;GZMA;DSCAML1 |
zinc ion binding | CA5A;RNF125;CA4A;TLL1;PGLYRP6;ADAM9;PGLYRP5;LNX1;NANOS1 |
EEA1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EEA1 here. Most of them are supplied by our site. Hope this information will be useful for your research of EEA1.
RAB5A; Stx6; ERBB2; RAB5B; SAMD9; Samd9l
- Q&As
- Reviews
Q&As (5)
Ask a questionEEA1 protein has been implicated in the pathogenesis of neurodegenerative disorders, including Alzheimer's disease and Parkinson's disease, where abnormal endosome trafficking may contribute to disease progression.
EEA1 protein expression and localization may serve as a potential diagnostic marker for certain neurodegenerative disorders, offering insights into disease pathology.
Research suggests that modulating EEA1 protein function may hold promise as a therapeutic approach for neurodegenerative disorders, although further investigation is needed.
EEA1 protein plays a critical role in the intracellular trafficking of pathogens, including viruses and bacteria, and its dysregulation can impact the outcome of infectious diseases.
In cancer cells, EEA1 protein expression levels can be altered, leading to abnormal endosome trafficking and potential implications for tumor growth and metastasis.
Customer Reviews (3)
Write a reviewIn protein electron microscopy structure analysis, the EEA1 protein demonstrates outstanding performance.
the EEA1 protein's versatility allows it to be effectively employed in various experimental designs, further enhancing its suitability for diverse research needs.
Their extensive knowledge and expertise can help troubleshoot issues or provide guidance on experimental design, enabling you to overcome obstacles and achieve your research goals.
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