This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes,;which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This;protein interacts with enhancer of zeste 2, the cytoplasmic tail of integrin beta7, immunodeficiency virus type 1;(HIV-1) MA protein, and histone deacetylase proteins. This protein mediates repression of gene activity through;histone deacetylation, and may act as a specific regulator of integrin function. Two transcript variants encoding;distinct isoforms have been identified for this gene.
EED; embryonic ectoderm development; polycomb protein EED; EED protein; EED_HUMAN; Embryonic ectoderm development isoform a; Embryonic ECTODERM development protein homolog; hEED; OTTHUMP00000235483; OTTHUMP00000235484; OTTHUMP00000235485; WAIT 1; WAIT-1; WAIT1; WD protein associating with integrin cytoplasmic tails 1