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EFS

  • Official Full Name

    embryonal Fyn-associated substrate

  • Overview

    The protein encoded by this gene contains a SH3 domain, which is known to be important in intracellular signal transduction. The protein encoded by a similiar gene in mice was shown to be able to bind to SH3 domain of protein-tyrosine kinases. The function of this gene is unknown. Two alternatively spliced variants have been described.
  • Synonyms

    EFS; embryonal Fyn-associated substrate; Cas scaffolding protein family member 3; CASS3; EFS1; EFS2; HEFS; SIN; CAS3; Embryonal Fyn associated substrate; signal transduction protein (SH3 containing);

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human EFS-3108H Recombinant Human EFS Protein, GST-tagged Wheat Germ GST
Human EFS-6699HCL Recombinant Human EFS 293 Cell Lysate HEK293 N/A
Human EFS-3849H Recombinant Human EFS Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human EFS-4238HF Recombinant Full Length Human EFS Protein, GST-tagged In Vitro Cell Free System GST 468 amino acids
Mouse EFS-5038M Recombinant Mouse EFS Protein Mammalian Cell His
Mouse EFS-2673M-B Recombinant Mouse EFS Protein Pre-coupled Magnetic Beads HEK293
Mouse Efs-2757M Recombinant Mouse Efs Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse EFS-2673M Recombinant Mouse EFS Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • EFS Related Articles

EFS involved in several pathways and played different roles in them. We selected most pathways EFS participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with EFS were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

EFS has several biochemical functions, for example, SH3 domain binding, protein binding, protein domain specific binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EFS itself. We selected most functions EFS had, and list some proteins which have the same functions with EFS. You can find most of the proteins on our site.

Function Related Protein
SH3 domain bindingSKAP1;FAM125A;RAD9A;SIRPA;WIPF3;LYN;PTTG2;OSTF1;DNM2
protein bindingPOLH;CISH;SH3PXD2B;EDC4;TDRKH;SNX33;SELS;BRAT1;BNIPL
protein domain specific bindingTADA3;NCK1;XPO1;STXBP1;VAPA;LAMP1;HIST4H4;TH;PTPN11

EFS has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EFS here. Most of them are supplied by our site. Hope this information will be useful for your research of EFS.

NUP155; SORBS2; FYN; ZNF417; OSTF1; TSSK1B; ABI2

Ramani, P; Nash, R; et al. Aurora kinase A is superior to Ki67 as a prognostic indicator of survival in neuroblastoma. HISTOPATHOLOGY 66:370-379(2015).
Coquenlorge, S; Duchalais, E; et al. Modulation of lipopolysaccharide-induced neuronal response by activation of the enteric nervous system. JOURNAL OF NEUROINFLAMMATION 11:-(2014).
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