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EGR3

  • Official Full Name

    early growth response 3

  • Overview

    This gene encodes a transcriptional regulator that belongs to the EGR family of C2H2-type zinc-finger proteins. It is an immediate-early growth response gene which is induced by mitogenic stimulation. The protein encoded by this gene participates in the transcriptional regulation of genes in controling biological rhythm. It may also play a role in a wide variety of processes including muscle development, lymphocyte development, endothelial cell growth and migration, and neuronal development. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Dec 2010]
  • Synonyms

    EGR3; early growth response 3; EGR-3; PILOT; early growth response protein 3; zinc finger protein pilot;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Sf9 Insect Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • His|T7
  • Myc
  • DDK
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human EGR3-398H Recombinant Human EGR3 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human EGR3-2083H Recombinant Human Early Growth Response 3 Sf9 Insect Cell N/A
Human EGR3-6970H Recombinant Human EGR3 protein, His & T7-tagged E.coli His/T7 Cys98~Ala363 (Accession # Q06889)
Human EGR3-3125H Recombinant Human EGR3 Protein, GST-tagged Wheat Germ GST
Human EGR3-243HCL Recombinant Human EGR3 lysate HEK293 N/A
Human EGR3-4270HF Recombinant Full Length Human EGR3 Protein, GST-tagged In Vitro Cell Free System GST 387 amino acids
Human EGR3-1826H Recombinant Human EGR3 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human EGR3-2855H Recombinant Human EGR3 protein, His-tagged E.coli His 1-186 aa
Human EGR3-2050H Recombinant Human EGR3 Protein (Cys98-Ala363), N-His tagged E.coli N-His Cys98-Ala363
Mouse EGR3-5054M Recombinant Mouse EGR3 Protein Mammalian Cell His
Mouse EGR3-2684M-B Recombinant Mouse EGR3 Protein Pre-coupled Magnetic Beads HEK293
Mouse Egr3-2762M Recombinant Mouse Egr3 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse EGR3-2684M Recombinant Mouse EGR3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat EGR3-2034R Recombinant Rat EGR3 Protein Mammalian Cell His
Rat EGR3-1691R Recombinant Rat EGR3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat EGR3-1691R-B Recombinant Rat EGR3 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish EGR3-757Z Recombinant Zebrafish EGR3 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • EGR3 Related Articles

EGR3 involved in several pathways and played different roles in them. We selected most pathways EGR3 participated on our site, such as Calcineurin-regulated NFAT-dependent transcription in lymphocytes, Hepatitis B, Viral carcinogenesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with EGR3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Calcineurin-regulated NFAT-dependent transcription in lymphocytesEGR2;CSF2;EGR1;BATF3;CTLA4;IKZF1;EGR4;DGKA;EGR3
Hepatitis BTGFB3;NFKB1;IL6;STAT1;PIK3R3;Ifna11;CCNA1;Ifna15;SMAD4
Viral carcinogenesisMAPKAPK2;DDX3X;RAC1;GTF2A1;ACTN4;SNW1;CCNE2;HDAC8;RB1

EGR3 has several biochemical functions, for example, DNA binding, metal ion binding, transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EGR3 itself. We selected most functions EGR3 had, and list some proteins which have the same functions with EGR3. You can find most of the proteins on our site.

Function Related Protein
DNA bindingZNF7;ZNF302;ADAR;POLA1;ZNF3;LASS4;SCML1;RPL7;SS18L1
metal ion bindingZFP775;PDE7A;ZFP30;PLCD3;ZNF624;AGFG2;MOB2;CNDP1;PLA2G4F
transcription factor activity, sequence-specific DNA bindingZFP583;TA;ZNF75D;ZNF215;L3MBTL1;POU5F2;HOXB6A;ARNTL1A;CREBZF

EGR3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EGR3 here. Most of them are supplied by our site. Hope this information will be useful for your research of EGR3.

Shin, H; Kwon, S; et al. The Transcription Factor Egr3 Is a Putative Component of the Microtubule Organizing Center in Mouse Oocytes. PLOS ONE 9:-(2014).
Darmanis, S; Cui, T; et al. Identification of Candidate Serum Proteins for Classifying Well-Differentiated Small Intestinal Neuroendocrine Tumors. PLOS ONE 8:-(2013).
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