EIF3I
-
Official Full Name
eukaryotic translation initiation factor 3, subunit I
-
Overview
The elF3I (eIF3-p36) is a subunit of eukaryotic translation initiation factor 3 (eIF3) complex that plays a central role in the protein translation initiation. The eIF3 consists of at least 10 subunits ranging from 35 to 170 kd. elF3-p36 is constitutively -
Synonyms
EIF3I; eukaryotic translation initiation factor 3, subunit I; EIF3S2, eukaryotic translation initiation factor 3, subunit 2 beta, 36kDa; eukaryotic translation initiation factor 3 subunit I; eIF3 beta; eIF3 p36; TRIP 1; eIF-3-beta; predicted prote;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Rat
- Zebrafish
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- N/A
- T7
- Involved Pathway
- Protein Function
- Interacting Protein
- EIF3I Related Articles
EIF3I involved in several pathways and played different roles in them. We selected most pathways EIF3I participated on our site, such as RNA transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with EIF3I were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| RNA transport | XPO5;SMN2;CLNS1A;SUMO2;NUP62;RANGAP1;NUP188;EIF1AY;SMN |
EIF3I has several biochemical functions, for example, poly(A) RNA binding, protein binding, contributes_to translation initiation factor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by EIF3I itself. We selected most functions EIF3I had, and list some proteins which have the same functions with EIF3I. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| poly(A) RNA binding | DHX37;UTP3;LUZP4;MRPS15;SAMD4;C1orf53;EIF2C3;APOBEC3C;NOLC1 |
| protein binding | PIH1D2;NPM1;CPSF7;AK3;TBXAS1;NPC2;AARSD1;SID4;SEPT1 |
| contributes_to translation initiation factor activity | EIF2B4;EIF3H;EIF3BA;EIF3F;EIF3M;EIF3I;EIF3C;EIF3S10;EIF3EB |
EIF3I has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EIF3I here. Most of them are supplied by our site. Hope this information will be useful for your research of EIF3I.
EIF3B; Eif3a; CLEC4G; gag-pol; SGK1; EIF3H; EIF1B; GH1; TFE3; MCC; HLA-B; EIF6; ACTB
- Q&As
- Reviews
Q&As (6)
Ask a questionThe protein is part of the EIF3 complex, which is involved in mRNA recognition and ligation by interacting with other EIF3 subunits, facilitating the post-transcriptional protein translation process.
EIF3I protein may be associated with cell cycle regulation. Some studies have shown that the expression level of EIF3I protein may vary at different stages of the cell cycle, but the specific regulatory mechanism needs further study.
Yes, the EIF3I protein can interact with other EIF3 subunits to form the EIF3 complex. The interaction between these subunits is to synergistically regulate the progress of protein synthesis.
Yes, there are differences in the expression levels of EIF3I protein in different tissues. For example, in some tumor tissues, the expression level of the EIF3I protein is significantly elevated.
EIF3I protein is associated with the occurrence and progression of a variety of diseases. For example, in some tumor cells, elevated levels of EIF3I protein are associated with enhanced proliferation, invasion, and metastasis of tumor cells. In addition, the EIF3I protein has been linked to some neurological diseases, such as Parkinson's disease.
There are currently no specific drugs designed to regulate the expression or function of the EIF3I protein. However, drug discovery targeting the EIF3 complex may affect the function of the EIF3I protein.
Customer Reviews (3)
Write a reviewStability of EIF3I is very good, and it can maintain a stable performance even after multiple uses, which gives me more confidence in the experimental results.
The band positions of EIF3I in Western blot were accurate and showed good specificity.
Their service attitude is very good, always patiently answer our questions.
Ask a Question for All EIF3I Products
Required fields are marked with *
My Review for All EIF3I Products
Required fields are marked with *
