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EIF4G3

  • Official Full Name

    eukaryotic translation initiation factor 4 gamma, 3

  • Overview

    Probable component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome. Thought to be a functional homolog of EIF4G1.
  • Synonyms

    EIF4G3; eukaryotic translation initiation factor 4 gamma, 3; eIF4G 3; eIF4GII; eIF-4G 3; eukaryotic translation initiation factor 4 gamma 3; eIF-4-gamma 3; eIF-4-gamma II;
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human EIF4G3-3212H Recombinant Human EIF4G3 Protein, GST-tagged Wheat Germ GST
Human EIF4G3-6645HCL Recombinant Human EIF4G3 293 Cell Lysate HEK293 N/A
Human EIF4G3-4298HF Recombinant Full Length Human EIF4G3 Protein, GST-tagged In Vitro Cell Free System GST 515 amino acids
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • EIF4G3 Related Articles
  • EIF4G3 Related Signal Pathway

EIF4G3 involved in several pathways and played different roles in them. We selected most pathways EIF4G3 participated on our site, such as RNA transport, Viral myocarditis, which may be useful for your reference. Also, other proteins which involved in the same pathway with EIF4G3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
RNA transportNUP153;PABPC1;SMN;POP1;EIF2B3;SARNP;THOC4;UBE2IB;SUMO1
Viral myocarditisHLA-DMB;ABL2;Casp3;EIF4G2;HLA-B;ITGB2L;HLA-G;CD28;HLA-DPB1

EIF4G3 has several biochemical functions, for example, RNA cap binding, poly(A) RNA binding, translation factor activity, RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EIF4G3 itself. We selected most functions EIF4G3 had, and list some proteins which have the same functions with EIF4G3. You can find most of the proteins on our site.

Function Related Protein
RNA cap bindingEIF4E;EIF4G3;EIF4E2;NCBP2;LARP1;NCBP1;EIF4A1;SNUPN
poly(A) RNA bindingZCRB1;EIF5B;RPL7;EWSR1;MRPL45;NIP7;DAP3;SSB;RNPS1
translation factor activity, RNA bindingEIF4H;EEF1D;EEF1A2;EIF4G3;EIF2S2;EIF4G2;CPEB1A;PPP1R2P9;ABCF1
translation initiation factor activityEIF1AXA;EIF4E3;EIF4E2RS1;EIF3EB;MTIF3;EIF1AXB;MTIF2;MCTS1;EIF4G3

EIF4G3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EIF4G3 here. Most of them are supplied by our site. Hope this information will be useful for your research of EIF4G3.

PABPC1; saicar; PKM; EIF3H; EIF4A1; NCBP1; EIF4A2; USP10; HSPB1; VAV2; q81kg1_bacan; yqeH; csgG; terD; MKNK1; 15-deoxy-delta(12,14; ere_dna

Jensik, PJ; Vargas, JD; et al. DEAF1 Binds Unmethylated and Variably Spaced CpG Dinucleotide Motifs. PLoS One 9:-(2014).
Hashimoto, R; Ikeda, M; et al. Common variants at 1p36 are associated with superior frontal gyrus volume. TRANSLATIONAL PSYCHIATRY 4:-(2014).
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