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EML4

  • Official Full Name

    echinoderm microtubule associated protein like 4

  • Overview

    EML4 is a 120 kDa microtubule-associated WD-repeat protein of the EMAP (echinoderm microtubule-associated protein) family. The expression of EML4 is necessary for correct intracellular microtubule network formation. EML4 protein expression is upregulated
  • Synonyms

    EML4; echinoderm microtubule associated protein like 4; C2orf2; echinoderm microtubule-associated protein-like 4; ELP120; ROPP120; ropp 120; restrictedly overexpressed proliferation-associated protein; EMAP-4; EMAPL4; FLJ10942; FLJ32318; DKFZp686P18118;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Human
  • Mouse
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Sf9 Insect Cell
  • Wheat Germ
  • GST
  • Myc
  • DDK
  • N/A
  • N
  • His
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human EML4-92H Active Recombinant Human EML4, GST-tagged Sf9 Insect Cell GST
Human EML4-3285H Recombinant Human EML4 Protein, GST-tagged Wheat Germ GST
Human EML4-6608HCL Recombinant Human EML4 293 Cell Lysate HEK293 N/A
Human EML4-1684H Recombinant Human EML4 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human EML4-4246HF Recombinant Full Length Human EML4 Protein, GST-tagged In Vitro Cell Free System GST 62 amino acids
Human EML4-2786H Recombinant Human EML4 Protein (Met1-Phe580), N-His tagged E.coli N-His Met1-Phe580
Mouse Eml4-2814M Recombinant Mouse Eml4 Protein, Myc/DDK-tagged HEK293T Myc/DDK
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • EML4 Related Articles

EML4 involved in several pathways and played different roles in them. We selected most pathways EML4 participated on our site, such as Non-small cell lung cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with EML4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Non-small cell lung cancerRXRB;ALK;RASSF5;RAF1;PIK3R3;AKT2;PIK3R5;STK4;CASP9

EML4 has several biochemical functions, for example, molecular_function. Some of the functions are cooperated with other proteins, some of the functions could acted by EML4 itself. We selected most functions EML4 had, and list some proteins which have the same functions with EML4. You can find most of the proteins on our site.

Function Related Protein
molecular_functionTMEM167;HSF5;FNDC7;TSTD2;FAM13B;XKR8.3;GM8898;LRRN4;PTGES3B

EML4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EML4 here. Most of them are supplied by our site. Hope this information will be useful for your research of EML4.

NEK6; ARIH2; ARL4D; 1-phosphatidyl-1d-myo-inositol 3,5-bisphosphate; ssrna_ug; TFEB; ILK; Nek9

Alese, OB; El-Rayes, BF; et al. Anaplastic lymphoma kinase (ALK) gene alteration in signet ring cell carcinoma of the gastrointestinal tract. THERAPEUTIC ADVANCES IN MEDICAL ONCOLOGY 7:56-62(2015).
Xiao, ZG; Sperl, B; et al. Metformin and salinomycin as the best combination for the eradication of NSCLC monolayer cells and their alveospheres (cancer stem cells) irrespective of EGFR, KRAS, EML4/ALK and LKB1 status. ONCOTARGET 5:12877-12890(2014).
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