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EMR3

Official Full Name

Egf-like Module Containing, Mucin-like, Hormone Receptor-like 3
Overview

This gene encodes a member of the class B seven-span transmembrane (TM7) receptor family expressed predominantly by cells of the immune system. Family members are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor (EGF)-like domains coupled to a TM7 domain via a mucin-like spacer domain. This gene is closely linked to the gene encoding egf-like molecule containing mucin-like hormone receptor 2 on chromosome 19. This protein may play a role in myeloid-myeloid interactions during immune and inflammatory responses.
Synonyms

EMR3; EGF-like module-containing mucin-like hormone receptor-like 3; EGF-like module receptor 3; egf-like module-containing mucin-like receptor 3;

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	EMR3-3293H	Recombinant Human EMR3 Protein	Wheat Germ	N/A		Inquiry
Human	EMR3-555HCL	Recombinant Human EMR3 cell lysate		N/A		Inquiry
Human	EMR3-4273HF	Recombinant Full Length Human EMR3 Protein	In Vitro Cell Free System		333 amino acids	Inquiry

Involved Pathway
Protein Function
Interacting Protein

EMR3 involved in several pathways and played different roles in them. We selected most pathways EMR3 participated on our site, such as Class B/2 (Secretin family receptors), GPCR ligand binding, GPCRs, Other, which may be useful for your reference. Also, other proteins which involved in the same pathway with EMR3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Class B/2 (Secretin family receptors)	RAMP2;PTH;PTHLH;FZD10;EMR1;SETD6;GHRH;ADCYAP1;CALCA
GPCR ligand binding	EMR4;ADM2A;GPR65;RLN3;CGA;GPBAR1;EDN2;OPN5;NPB
GPCRs, Other	S1PR1;GPR61;EMR3;EMR2;OR10A5;VMN1R49;VMN1R48;CELSR1;ADORA3
Signal Transduction	SOX13;RDH10;FFAR3;GPR39;ADH8B;RHOT1;ARHGAP4;ARHGAP12;GPR37L1
Signaling by GPCR	VIP;CXCR7B;GPR77;OR52J3;INSL5;ANXA1B;PTHLHA;PYYA;GPR132B

EMR3 has several biochemical functions, for example, G-protein coupled receptor activity, calcium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EMR3 itself. We selected most functions EMR3 had, and list some proteins which have the same functions with EMR3. You can find most of the proteins on our site.

Function	Related Protein
G-protein coupled receptor activity	OLFR688;TAS2R113;GPR75;OLFR507;TAAR10B;EDNRAA;TAAR14G;RGRB;TAAR12J
calcium ion binding	CABP5;ANXA13;CETN2;TESC;S100A12;PADI3;CUBN;DNASE1L3;PCDHGA1

EMR3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EMR3 here. Most of them are supplied by our site. Hope this information will be useful for your research of EMR3.