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EMX2

  • Official Full Name

    empty spiracles homeobox 2

  • Overview

    This gene encodes a homeobox-containing transcription factor that is the homolog to the empty spiracles gene in Drosophila. Research on this gene in humans has focused on its expression in three tissues: dorsal telencephalon, olfactory neuroepithelium, and urogenetial system. It is expressed in the dorsal telencephalon during development in a low rostral-lateral to high caudal-medial gradient and is proposed to pattern the neocortex into defined functional areas. It is also expressed in embryonic and adult olfactory neuroepithelia where it complexes with eukaryotic translation initiation factor 4E (eIF4E) and possibly regulates mRNA transport or translation. In the developing urogenital system, it is expressed in epithelial tissues and is negatively regulated by HOXA10. Alternative splicing results in multiple transcript variants encoding distinct proteins.
  • Synonyms

    EMX2; empty spiracles homeobox 2; empty spiracles homolog 2 (Drosophila); homeobox protein EMX2; empty spiracles homolog 2; empty spiracles-like protein 2;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human EMX2-3296H Recombinant Human EMX2 Protein, GST-tagged Wheat Germ GST
Human EMX2-6604HCL Recombinant Human EMX2 293 Cell Lysate HEK293 N/A
Human EMX2-4283HF Recombinant Full Length Human EMX2 Protein, GST-tagged In Vitro Cell Free System GST 252 amino acids
Mouse EMX2-5190M Recombinant Mouse EMX2 Protein Mammalian Cell His
Mouse EMX2-2783M-B Recombinant Mouse EMX2 Protein Pre-coupled Magnetic Beads HEK293
Mouse EMX2-2783M Recombinant Mouse EMX2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque EMX2-1469R Recombinant Rhesus monkey EMX2 Protein, His-tagged Mammalian Cell His
Rhesus Macaque EMX2-1294R Recombinant Rhesus Macaque EMX2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque EMX2-1294R-B Recombinant Rhesus Macaque EMX2 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish EMX2-8872Z Recombinant Zebrafish EMX2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • EMX2 Related Articles
  • EMX2 Related Research Area

EMX2 involved in several pathways and played different roles in them. We selected most pathways EMX2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with EMX2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

EMX2 has several biochemical functions, for example, protein binding, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EMX2 itself. We selected most functions EMX2 had, and list some proteins which have the same functions with EMX2. You can find most of the proteins on our site.

Function Related Protein
protein bindingCOMMD2;THOC7;AXIN2;MYO5B;POT1;NELL2;USP36;KHK;NUDT1
sequence-specific DNA bindingNKX2.5;SREBF1;HOXA7;DHARMA;GLI2A;FOXN4;FOXD2;LHX9;HOXA11B

EMX2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EMX2 here. Most of them are supplied by our site. Hope this information will be useful for your research of EMX2.

EIF4E

Brancaccio, M; Pivetta, C; et al. Emx2 and Foxg1 Inhibit Gliogenesis and Promote Neuronogenesis. STEM CELLS 28:1206-1218(2010).
Ostrer, H; Huang, HY; et al. A cellular study of human testis development. SEXUAL DEVELOPMENT 1:286-292(2007).
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