EPB41
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Official Full Name
erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
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Overview
The protein encoded by this gene, together with spectrin and actin, constitute the red cell membrane cytoskeletal network. This complex plays a critical role in erythrocyte shape and deformability. Mutations in this gene are associated with type 1 elliptocytosis (EL1). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. -
Synonyms
EPB41; erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked); EL1; protein 4.1; 4.1R; P4.1; EPB4.1; band 4.1; erythrocyte surface protein band 4.1; HE;
- Recombinant Proteins
- Cell & Tissue Lysates
- Chicken
- Human
- Mouse
- E.coli
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- Myc
- DDK
- N/A
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | EPB41-3351H | Recombinant Human EPB41 Protein, GST-tagged | Wheat Germ | GST |
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| Human | EPB41-28575TH | Recombinant Human EPB41 | Wheat Germ | N/A | 720 amino acids |
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| Human | EPB41-560HCL | Recombinant Human EPB41 cell lysate | N/A |
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| Human | EPB41-157HF | Recombinant Full Length Human EPB41 Protein | In Vitro Cell Free System | 720 amino acids |
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| Human | EPB41-468H | Recombinant Human EPB41 Protein, His-tagged | E.coli | His | Met210~Lys497 |
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| Human | EPB41-3551H | Recombinant Human EPB41 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Myc/DDK |
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| Human | EPB41-4350HF | Recombinant Full Length Human EPB41 Protein, GST-tagged | In Vitro Cell Free System | GST | 720 amino acids |
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| Mouse | Epb41-469M | Recombinant Mouse Epb41 Protein, His-tagged | E.coli | His | Met211~Lys498 |
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| Chicken | EPB41-4036C | Recombinant Chicken EPB41 | Mammalian Cell | His |
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- Involved Pathway
- Protein Function
- Interacting Protein
EPB41 involved in several pathways and played different roles in them. We selected most pathways EPB41 participated on our site, such as Tight junction, which may be useful for your reference. Also, other proteins which involved in the same pathway with EPB41 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Tight junction | MYH9;MYH1B;ACTN4;EPB41;OCLNA;EPB41L1;SHROOM1;YBX3;EPB41L3A |
EPB41 has several biochemical functions, for example, 1-phosphatidylinositol binding, actin binding, calmodulin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EPB41 itself. We selected most functions EPB41 had, and list some proteins which have the same functions with EPB41. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| 1-phosphatidylinositol binding | SNAP91;PLEKHA4;SYT1;PLEKHA2;ZFYVE16;PICALM;ZFYVE1;PICALMB;SCARB1 |
| actin binding | MICAL2B;CAMK2B;SPATA31;LMOD1;KCNMA1;MYH1;ESPN;MYO6;DNASE1 |
| calmodulin binding | CALD1B;PCP4;CAMK1GA;ITPKB;CAMK2D;DDX5;MYH1E;CAMK1D;CAMK2D2 |
| protein binding | HP1BP3;RABAC1;NDRG1;SNRPE;OTX1;NUPL1;PCGF1;COP1;SDCBP2 |
| spectrin binding | PTPRN;CAMSAP1;STX4A;KIF3A;PDE6G;GNB1;GBP1;USH1C;USH1G |
| structural constituent of cytoskeleton | TUBB1;SPTAN1;TUBB5;TUBA8L;DSP;EPB41L4B;CYLC2;TUBB;TPM1 |
EPB41 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EPB41 here. Most of them are supplied by our site. Hope this information will be useful for your research of EPB41.
CASK; 4504555; CLIC1; PSMA7; PFAS; SNX3; SNRNP200; NUP155; ATP5L; PNP; HPRT1; GOT2; CSTB; GYPC; TPM2; TXN; COX5B; PCNA
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