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EPB42

  • Official Full Name

    erythrocyte membrane protein band 4.2

  • Overview

    Erythrocyte membrane protein band 4.2 is an ATP-binding protein which may regulate the association of protein 3 with ankyrin. It probably has a role in erythrocyte shape and mechanical property regulation. Mutations in the EPB42 gene are associated with recessive spherocytic elliptocytosis and recessively transmitted hereditary hemolytic anemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
  • Synonyms

    EPB42; erythrocyte membrane protein band 4.2; Erythrocyte surface protein band 4.2; MGC116735; MGC116737; PA; EPB42_HUMAN; Erythrocyte protein 4.2; P4.2; SPH5; OTTHUMP00000161294;
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human EPB42-26437TH Recombinant Human EPB42 Wheat Germ N/A 99 amino acids
Human EPB42-1406H Recombinant Human EPB42 protein, His & GST-tagged E.coli His/GST Leu475~Ala686 (Accession # P16452)
Human EPB42-3361H Recombinant Human EPB42 Protein, GST-tagged Wheat Germ GST
Human EPB42-564HCL Recombinant Human EPB42 cell lysate N/A
Human EPB42-4267HF Recombinant Full Length Human EPB42 Protein, GST-tagged In Vitro Cell Free System GST 619 amino acids
  • Involved Pathway
  • Protein Function
  • Interacting Protein

EPB42 involved in several pathways and played different roles in them. We selected most pathways EPB42 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with EPB42 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

EPB42 has several biochemical functions, for example, ATP binding, protein binding, protein-glutamine gamma-glutamyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by EPB42 itself. We selected most functions EPB42 had, and list some proteins which have the same functions with EPB42. You can find most of the proteins on our site.

Function Related Protein
ATP bindingSTK36;CLK4B;P2RX4B;DDX53;PKM2;ABCC3;HSP104;GRK6;ACVR1C
protein bindingTFF2;BTBD1;CDKAL1;ADCYAP1;PDE4A;TNIP1;KCNIP2;ITGB1BP1;CBX8
protein-glutamine gamma-glutamyltransferase activityF13A1B;TGM1;TGM5;TGM4;EPB42;F13A1A.1;EPB4.2;TGM1L4;F13A1
structural constituent of cytoskeletonTUBA3C;TLN1;BICD1;YEATS4;SORBS2;KRT71;NEFL;ATXN1;TNNT2A

EPB42 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EPB42 here. Most of them are supplied by our site. Hope this information will be useful for your research of EPB42.

SPINK7; ZNF16; MAPK14

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