EPX
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Official Full Name
eosinophil peroxidase
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Overview
This gene is a member of the peroxidase gene family and is expressed in eosinophils. The encoded precursor protein is processed into covalently attached heavy and light chains to form the mature enzyme, which functions as an oxidant. The enzyme is released at sites of parasitic infection or allergen stimulation to mediate lysis of protozoa or parasitic worms. The gene is found in a cluster of three peroxidase genes at chromosome 17q23. Mutations in this gene result in eosinophil peroxidase deficiency. -
Synonyms
EPX; eosinophil peroxidase; EPO; EPP; EPX PEN; Eosinophil peroxidase [Precursor]; EPER; PERE; EPX-PEN;
- Recombinant Proteins
- Cell & Tissue Lysates
- Native Proteins
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- CHO
- E. coli
- HEK293
- Human Eosinophils
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- N/A
- N
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
---|---|---|---|---|---|---|
Human | EPX-3434H | Recombinant Human EPX Protein, GST-tagged | Wheat Germ | GST | ||
Human | EPX-6573HCL | Recombinant Human EPX 293 Cell Lysate | HEK293 | N/A | ||
Human | EPX-1862H | Native Human Eosinophil Peroxidase | Human Eosinophils | N/A | ||
Human | EPX-4416HF | Recombinant Full Length Human EPX Protein, GST-tagged | In Vitro Cell Free System | GST | 715 amino acids | |
Human | EPX-8107H | Native Human Eosinophil Peroxidase | Human Eosinophils | N/A | ||
Human | EPX-51H | Recombinant Human EPX Protein, His-tagged | E. coli | His | Arg140~Gly250 | |
Mouse | EPX-5272M | Recombinant Mouse EPX Protein | Mammalian Cell | His | ||
Mouse | EPX-2834M-B | Recombinant Mouse EPX Protein Pre-coupled Magnetic Beads | HEK293 | |||
Mouse | Epx-905M | Recombinant Mouse Epx Protein, His-tagged | CHO | N-His | Gln19-Arg300 | |
Mouse | EPX-2834M | Recombinant Mouse EPX Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Mouse | EPX-5257M | Recombinant Mouse EPX Protein, His-GST-tagged | E. coli | His-GST | Gln19~Arg300 |
- Involved Pathway
- Protein Function
- Interacting Protein
- EPX Related Articles
EPX involved in several pathways and played different roles in them. We selected most pathways EPX participated on our site, such as Asthma, which may be useful for your reference. Also, other proteins which involved in the same pathway with EPX were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Asthma | HLA-DRB1;MS4A2;FCER1A;EPX;HLA-DQA1;CD40LG;HLA-DRB5;IL4;HLA-DRB3 |
EPX has several biochemical functions, for example, heme binding, metal ion binding, peroxidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by EPX itself. We selected most functions EPX had, and list some proteins which have the same functions with EPX. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
heme binding | CYP51;NGB;ABCB6;CYP4T8;Adgb;CYP8B3;HBE;CYP11B2;CYP2D10 |
metal ion binding | ZDHHC18A;TRMT1;ZMYND19;CYP2K16;MORC1;ZNF563;POMT2;ALOX5A;ZSCAN4C |
peroxidase activity | GPX1B;GPX8;GPX4B;MPX;PXDN;GPX7;GPX5;MGST3;GPX1A |
EPX has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EPX here. Most of them are supplied by our site. Hope this information will be useful for your research of EPX.
NCK1; PLCG1; PIK3R1
- Q&As
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