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TFAP2C

Official Full Name

transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
Overview

The protein encoded by this gene is a sequence-specific DNA-binding transcription factor involved in the activation of several developmental genes. The encoded protein can act as either a homodimer or heterodimer with other family members and is induced during retinoic acid-mediated differentiation. It plays a role in the development of the eyes, face, body wall, limbs, and neural tube.
Synonyms

TFAP2C; transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma); transcription factor AP 2 gamma (activating enhancer binding protein 2 gamma); transcription factor AP-2 gamma; AP2 GAMMA; ERF1; estrogen receptor factor 1; hAP 2g; TFA;

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	TFAP2C-7347H	Recombinant Human TFAP2C, His tagged	E.coli	His	Inquiry
Human	TFAP2C-1766HCL	Recombinant Human TFAP2C cell lysate		N/A	Inquiry
Mouse	Tfap2c-6375M	Recombinant Mouse Tfap2c Protein, Myc/DDK-tagged	HEK293T	Myc/DDK	Inquiry
Zebrafish	TFAP2C-1875Z	Recombinant Zebrafish TFAP2C	Mammalian Cell	His	Inquiry

Involved Pathway
Protein Function
Interacting Protein
TFAP2C Related Research Area

TFAP2C involved in several pathways and played different roles in them. We selected most pathways TFAP2C participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with TFAP2C were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

TFAP2C has several biochemical functions, for example, DNA binding, RNA polymerase II distal enhancer sequence-specific DNA binding, RNA polymerase II regulatory region sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TFAP2C itself. We selected most functions TFAP2C had, and list some proteins which have the same functions with TFAP2C. You can find most of the proteins on our site.

Function	Related Protein
DNA binding	PAX4;ZBED2;ASCL1;POLR1A;ZFP580;HIST2H2L;ZNF446;BSX;SP140
RNA polymerase II distal enhancer sequence-specific DNA binding	SOX10;REL;CDX2;MEOX2;NR5A2;NFE2L1;MIXL1;BACH2;TFAP2C
RNA polymerase II regulatory region sequence-specific DNA binding	CUX1;GATA1A;ZBTB16A;ZNF549;ZSCAN2;SP5;RXRG;DMRT2;PRKCBP1L
core promoter binding	E2F8;DHX36;CRY1;NEUROG3;AGO1;MYOG;IFI16;SFPQ;MYOD1
protein binding	FCRL2;RINL;AGPAT5;TMEM147;CTNNAL1;COL3A1;DNAJC5B;AP2A1;FAM20C
protein dimerization activity	MEF2AA;NEUROD4;NPAS1;PEF1;MESPBB;POLR2J;STAT3;MYCLB;SCXA
transcription factor activity, sequence-specific DNA binding	PBX2;GTF2H4;ZNF548;BCL6;MEF2D;TFCP2L1;USF2;TRPS1;TEAD4
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	MESP1;GABPA;SFPI1;TFE3;CREB3L2;NR4A3;ETV4;MYBL2;EHF
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding	SREBF2;ZFP90;SNAI1;ZFP746;NFATC2;MYPOP;ZFPM2A;ATF3;PROX1B

TFAP2C has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TFAP2C here. Most of them are supplied by our site. Hope this information will be useful for your research of TFAP2C.

UBE2I; human_frem2_promoter_region_probe; RARA; CITED2; EYA2; IKBKB; LDLRAD4; LAMA5; ACTN4; NR1I2

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G1 (Restriction) Checkpoints

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