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ERRFI1

  • Official Full Name

    ERBB receptor feedback inhibitor 1

  • Overview

    ERRFI1 is a cytoplasmic protein whose expression is upregulated with cell growth (Wick et al., 1995 (PubMed 7641805)).;It shares significant homology with the protein product of rat gene-33, which is induced during cell stress and;mediates cell signaling (Makkinje et al., 2000 (PubMed 10749885); Fiorentino et al., 2000 (PubMed 11003669)).
  • Synonyms

    ERRFI1; ERBB receptor feedback inhibitor 1; GENE 33; MIG 6; RALT; mitogen-inducible gene 6 protein; receptor-associated late transducer; MIG6; MIG-6; GENE-33;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ERRFI1-3491H Recombinant Human ERRFI1 Protein, GST-tagged Wheat Germ GST
Human ERRFI1-6542HCL Recombinant Human ERRFI1 293 Cell Lysate HEK293 N/A
Human ERRFI1-4607HF Recombinant Full Length Human ERRFI1 Protein, GST-tagged In Vitro Cell Free System GST 462 amino acids
Rat ERRFI1-2145R Recombinant Rat ERRFI1 Protein Mammalian Cell His
Rat ERRFI1-1802R-B Recombinant Rat ERRFI1 Protein Pre-coupled Magnetic Beads HEK293
Rat ERRFI1-1802R Recombinant Rat ERRFI1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque ERRFI1-1498R Recombinant Rhesus monkey ERRFI1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque ERRFI1-1323R-B Recombinant Rhesus Macaque ERRFI1 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque ERRFI1-1323R Recombinant Rhesus Macaque ERRFI1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish ERRFI1-5423Z Recombinant Zebrafish ERRFI1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • ERRFI1 Related Articles

ERRFI1 involved in several pathways and played different roles in them. We selected most pathways ERRFI1 participated on our site, such as EGFR1 Signaling Pathway, Signaling Pathways in Glioblastoma, which may be useful for your reference. Also, other proteins which involved in the same pathway with ERRFI1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
EGFR1 Signaling PathwayCEACAM1;SH2D3C;ZNF259;PTK6;RALBB;PLSCR1;EPS8;PTPN12;KLF11
Signaling Pathways in Glioblastoma

ERRFI1 has several biochemical functions, for example, GTPase activator activity, SH3 domain binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ERRFI1 itself. We selected most functions ERRFI1 had, and list some proteins which have the same functions with ERRFI1. You can find most of the proteins on our site.

Function Related Protein
GTPase activator activityASAP2;TBC1D5;ADAP2;ASAP3;SMAP1;ARHGAP6;ARHGAP44;RAB3GAP2;RIC8
SH3 domain bindingSH3BP5;NCF1;GJA1;SKAP1;DPYSL3;MVB12A;GRIK5;ADAM15;CD2AP
protein bindingSUV420H2;BLVRA;QKI;UPF1;NCKIPSD;AGRN;KRT86;SPOP;DDAH2
protein kinase bindingNEK9;CALM1;PARP1;PTK2;FOXO3;TSACC;TELO2;PARN;SUFU
small GTPase bindingFGD5;FGD3;TSC2;FGD1;FLNA;FGD2;FGD6;PEX5;ERRFI1

ERRFI1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ERRFI1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ERRFI1.

GRB2; EGFR; SFN; ERBB2

Liu, J; Cho, SN; et al. ErbB2 Pathway Activation upon Smad4 Loss Promotes Lung Tumor Growth and Metastasis. CELL REPORTS 10:1599-1613(2015).
Chen, YC; Colvin, ES; et al. Mig6 haploinsufficiency protects mice against streptozotocin-induced diabetes. DIABETOLOGIA 57:2066-2075(2014).
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