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ESCO2

Official Full Name

establishment of cohesion 1 homolog 2 (S. cerevisiae)
Overview

This gene encodes a protein that may have acetyltransferase activity and may be required for the establishment of sister chromatid cohesion during the S phase of mitosis. Mutations in this gene have been associated with Roberts syndrome.
Synonyms

ESCO2; establishment of cohesion 1 homolog 2 (S. cerevisiae); RBS, Roberts syndrome; N-acetyltransferase ESCO2; EFO2; CTF7, S. CEREVISIAE, HOMOLOG OF, 2; ECO1 homolog 2; ECO1, S. CEREVISIAE, HOMOLOG OF, 2; ESO1, S. POMBE, HOMOLOG OF, 2; ESTABLISHMENT FACTOR ORTHOLOG 2; Establishment of cohesion 1 homolog 2; N acetyltransferase ESCO2; RBS; Roberts syndrome; 2410004I17Rik;

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Zebrafish

Source

E.coli
HEK293
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	ESCO2-01H	Recombinant Human ESCO2, GST-tagged	E.coli	GST	2-352a.a.	Inquiry
Human	ESCO2-3497H	Recombinant Human ESCO2 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	ESCO2-4699HF	Recombinant Full Length Human ESCO2 Protein, GST-tagged	In Vitro Cell Free System	GST	601 amino acids	Inquiry
Mouse	ESCO2-5319M	Recombinant Mouse ESCO2 Protein	Mammalian Cell	His		Inquiry
Mouse	ESCO2-2862M	Recombinant Mouse ESCO2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	ESCO2-2862M-B	Recombinant Mouse ESCO2 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	ESCO2-1159Z	Recombinant Zebrafish ESCO2	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
ESCO2 Related Articles

ESCO2 involved in several pathways and played different roles in them. We selected most pathways ESCO2 participated on our site, such as Cell Cycle, Cell Cycle, Mitotic, Establishment of Sister Chromatid Cohesion, which may be useful for your reference. Also, other proteins which involved in the same pathway with ESCO2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Cell Cycle	MSH4;CDK2;NEDD1;CLASP1;SGOL1;ACTR1A;ESCO2;CDH1-A;CCNB2
Cell Cycle, Mitotic	H3F3D;DULLARD;CEP72;ZWILCH;RANGAP1B;CENPH;E2F2;NUF2;GORASP2
Establishment of Sister Chromatid Cohesion	CDCA5;STAG2;ESCO1;ESCO2;WAPAL;STAG1;PDS5B;PDS5A
S Phase	MYCA;GINS3;ESCO2;GINS2;ESCO1;GINS4;GINS1

ESCO2 has several biochemical functions, for example, lysine N-acetyltransferase activity, acting on acetyl phosphate as donor, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ESCO2 itself. We selected most functions ESCO2 had, and list some proteins which have the same functions with ESCO2. You can find most of the proteins on our site.

Function	Related Protein
lysine N-acetyltransferase activity, acting on acetyl phosphate as donor	NAT8;CEACAM21;EP300;NAT8B;ESCO2;RHBDL1;KAT2B
metal ion binding	LNPB;SIRT4;RARGB;ING5B;ITGA2B;ZFP523;NAALADL1;NDUFV2;NOTCH1A

ESCO2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ESCO2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ESCO2.

Lrrcc1; YEATS4; USF1; S100A4; Bmpr1a; NCAPD3; MATR3; Cct2; Rpl35; Poc1a; CBX8

Hammerschmidt, K; Whelan, G; et al. Mice lacking the cerebral cortex develop normal song: Insights into the foundations of vocal learning. SCIENTIFIC REPORTS 5:-(2015).

Rockwell, N; Weech, A; et al. NOVEL CHROMATIN REGULATORY ACTIVITY OF ESCO2 IN CANCER AND NEURAL DEVELOPMENT. NEURO-ONCOLOGY 16:-(2014).