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ESD

Official Full Name

esterase D
Overview

This gene encodes a serine hydrolase that belongs to the esterase D family. The encoded enzyme is active toward numerous substrates including O-acetylated sialic acids, and it may be involved in the recycling of sialic acids. This gene is used as a genetic marker for retinoblastoma and Wilsons disease.
Synonyms

ESD; esterase D; esterase D/formylglutathione hydrolase; S-formylglutathione hydrolase; S formylglutathione hydrolase; EC 3.1.2.12; Es-10; Es10; ESTD_HUMAN; Esterase 10; Esterase D formylglutathione hydrolase; FGH; FGH, included; FLJ11763; MGC139609; OTTHUMP00000018374; OTTHUMP00000040929; S-formylglutathione hydrolase, included; Sid 478; sid478;

Type

Cell & Tissue Lysates
Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Mouse
Rat
Rhesus Macaque
Zebrafish

Source

E.coli
HEK293
HEK293T
Human
In Vitro Cell Free System
Mammalian Cell
Mammalian cells
Wheat Germ

Tag

Fc|His
Flag
GST
His
His (Fc)
Avi
Myc
DDK
MYC
N/A
N

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	ESD-6541HCL	Recombinant Human ESD 293 Cell Lysate	HEK293	N/A		$298 / 20ug
Human	ESD-376H	Recombinant Human Esterase D/Formylglutathione Hydrolase	E.coli	N/A		Inquiry
Human	ESD-1682H	Recombinant Human Esterase D, His-tagged	Human	His		Inquiry
Human	ESD-12554H	Recombinant Human ESD, GST-tagged	E.coli	GST	1-282a.a.	$319 / 25ug
Human	ESD-3498H	Recombinant Human ESD Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	ESD-566H	Recombinant Human ESD, His tagged	E.coli	Fc/His		Inquiry
Human	ESD-27973TH	Recombinant Human ESD, His-tagged	E.coli	His		Inquiry
Human	ESD-1661H	Recombinant Human ESD Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK		Inquiry
Human	ESD-2223H	Recombinant Human ESD Protein	E.coli	N/A		Inquiry
Human	ESD-1173HFL	Recombinant Full Length Human ESD Protein, C-Flag-tagged	Mammalian cells	Flag		Inquiry
Human	ESD-1443H	Recombinant Human ESD Protein, His-tagged	E.coli	N-His	Ala2-Ala282	Inquiry
Human	ESD-4703HF	Recombinant Full Length Human ESD Protein, GST-tagged	In Vitro Cell Free System	GST	282 amino acids	Inquiry
Human	ESD-867H-B	Recombinant Human ESD Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Human	ESD-867H	Recombinant Human ESD Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Human	ESD-3010H	Recombinant Human ESD Protein (Met1-Ala282), N-His tagged	E.coli	N-His	Met1-Ala282	Inquiry
Mouse	ESD-5320M	Recombinant Mouse ESD Protein	Mammalian Cell	His		Inquiry
Mouse	Esd-5652M	Recombinant Mouse Esd Protein (Met1-Ala282), N-His tagged	E.coli	N-His	Met1-Ala282	Inquiry
Mouse	ESD-2863M-B	Recombinant Mouse ESD Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	ESD-2863M	Recombinant Mouse ESD Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	Esd-1444M	Recombinant Mouse Esd Protein, His-tagged	E.coli	N-His	Ala2-Ala282	Inquiry
Mouse	Esd-975M	Recombinant Mouse Esd Protein, MYC/DDK-tagged	HEK293T	MYC/DDK		Inquiry
Rat	ESD-2147R	Recombinant Rat ESD Protein	Mammalian Cell	His		Inquiry
Rat	ESD-1804R-B	Recombinant Rat ESD Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rat	ESD-1804R	Recombinant Rat ESD Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rhesus Macaque	ESD-1503R	Recombinant Rhesus monkey ESD Protein, His-tagged	Mammalian Cell	His		Inquiry
Rhesus Macaque	ESD-1328R	Recombinant Rhesus Macaque ESD Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rhesus Macaque	ESD-1328R-B	Recombinant Rhesus Macaque ESD Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	ESD-2532Z	Recombinant Zebrafish ESD	Mammalian Cell	His		Inquiry
Chicken	ESD-5150C	Recombinant Chicken ESD	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
ESD Related Articles

ESD involved in several pathways and played different roles in them. We selected most pathways ESD participated on our site, such as Carbon metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with ESD were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Carbon metabolism	GOT2B;DLAT;CPS1;ENO1B;PGK1;PFKP;RPE;PFKMB;GPR19

ESD has several biochemical functions, for example, S-formylglutathione hydrolase activity, carboxylic ester hydrolase activity, hydrolase activity, acting on ester bonds. Some of the functions are cooperated with other proteins, some of the functions could acted by ESD itself. We selected most functions ESD had, and list some proteins which have the same functions with ESD. You can find most of the proteins on our site.

Function	Related Protein
S-formylglutathione hydrolase activity
carboxylic ester hydrolase activity	ABHD4;ESD;ACOT9;ABHD2A;CES1C;LYPLA2;CES3A;CES1;ABHD2
hydrolase activity, acting on ester bonds	SMFN;ACY3.1;LIPK;PTER;PGAP3;ESD;IAH1;ENDOU2;LIPM
methylumbelliferyl-acetate deacetylase activity	CES2;ESD;CES1
protein binding	VASNA;RAB2B;CAND1;ARHGAP24;CAP2;EIF4E;KIT;ENTPD3;MRAP

ESD has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ESD here. Most of them are supplied by our site. Hope this information will be useful for your research of ESD.

FSD2; MCC; HLA-B; DDA1; TRAF6; PLCG2; CRK; GRB2; VCAM1; HDAC1

De Vitis, V; Guidi, B; et al. Marine Microorganisms as Source of Stereoselective Esterases and Ketoreductases: Kinetic Resolution of a Prostaglandin Intermediate. MARINE BIOTECHNOLOGY 17:144-152(2015).

Gunter, EA; Shkryl, YN; et al. Cell-wall polysaccharide composition and glycanase activity of Silene vulgaris callus transformed with rolB and rolC genes. CARBOHYDRATE POLYMERS 118:52-59(2015).