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ESPN

Official Full Name

espin
Overview

This gene encodes a multifunctional actin-bundling protein. It plays a major role in regulating the organization, dimensions, dynamics, and signaling capacities of the actin filament-rich, microvillus-type specializations that mediate sensory transduction in various mechanosensory and chemosensory cells. Mutations in this gene are associated with autosomal recessive neurosensory deafness, and autosomal dominant sensorineural deafness without vestibular involvement.
Synonyms

ESPN; espin; deafness, autosomal recessive 36 , DFNB36; ectoplasmic specialization protein; autosomal recessive deafness type 36 protein; DFNB36; LP2654; DKFZp434A196; DKFZp434G2126;

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Rat
Zebrafish

Source

HEK293
HEK293T
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
Myc
DDK

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	ESPN-3503H	Recombinant Human ESPN Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	ESPN-4412H	Recombinant Human ESPN Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK		Inquiry
Human	ESPN-4711HF	Recombinant Full Length Human ESPN Protein, GST-tagged	In Vitro Cell Free System	GST	854 amino acids	Inquiry
Mouse	Espn-2871M	Recombinant Mouse Espn Protein, Myc/DDK-tagged	HEK293T	Myc/DDK		Inquiry
Rat	ESPN-2150R	Recombinant Rat ESPN Protein	Mammalian Cell	His		Inquiry
Rat	ESPN-1807R	Recombinant Rat ESPN Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	ESPN-1807R-B	Recombinant Rat ESPN Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	ESPN-6670Z	Recombinant Zebrafish ESPN	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
ESPN Related Articles

ESPN involved in several pathways and played different roles in them. We selected most pathways ESPN participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ESPN were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

ESPN has several biochemical functions, for example, actin binding, actin filament binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ESPN itself. We selected most functions ESPN had, and list some proteins which have the same functions with ESPN. You can find most of the proteins on our site.

Function	Related Protein
actin binding	MYRIP;CCR5;LCP1;SMTNL;ADD1;MTSS1LA;PHACTR3A;TNS1;HIP1RB
actin filament binding	PICK1;MYO1D;MARCKS;FSCN1A;GAS2L2;NEBL;MYO1E;ABL2;FLNA

ESPN has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ESPN here. Most of them are supplied by our site. Hope this information will be useful for your research of ESPN.

Lee, JJ; Kang, CK; et al. Evaluation of shear bond strength between dual cure resin cement and zirconia ceramic after thermocycling treatment. JOURNAL OF ADVANCED PROSTHODONTICS 7:1-7(2015).

Al-Bahrani, A; Patel, D; et al. Using ESPN 30 for 30 to Teach Economics. SOUTHERN ECONOMIC JOURNAL 81:829-842(2015).