Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953 Learn More

ETS2

Official Full Name

v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)
Overview

This gene encodes a transcription factor which regulates genes involved in development and apoptosis. The encoded;protein is also a protooncogene and shown to be involved in regulation of telomerase. A pseudogene of this gene is;located on the X chromosome. Alternative splicing results in multiple transcript variants.
Synonyms

ETS2; v-ets erythroblastosis virus E26 oncogene homolog 2 (avian); v ets avian erythroblastosis virus E26 oncogene homolog 2; protein C-ets-2; C ets 2 protein; ETS2_HUMAN; ETS2IT1; Oncogene ETS2; v ets avian erythroblastosis virus E2 oncogene homolog 2; V ets erythroblastosis virus E26 oncogene homolog 2; oncogene ETS-2; v-ets avian erythroblastosis virus E2 oncogene homolog 2; v-ets avian erythroblastosis virus E26 oncogene homolog 2;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Mouse
Zebrafish

Source

E.coli
HEK293
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	ETS2-247H	Recombinant Human ETS2, His-tagged	E.coli	His	1-469aa	Inquiry
Human	ETS2-902H	Recombinant Human ETS2 Protein, His-tagged	E.coli	His		Inquiry
Human	ETS2-3529H	Recombinant Human ETS2 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	ETS2-12569H	Recombinant Human ETS2, GST-tagged	E.coli	GST	84-444a.a.	$319 / 25ug
Human	ETS2-6525HCL	Recombinant Human ETS2 293 Cell Lysate	HEK293	N/A		Inquiry
Human	ETS2-0423H	Recombinant Human ETS2 protein, His-tagged	E.coli	His	84-444 aa	$319 / 25ug
Human	ETS2-4749HF	Recombinant Full Length Human ETS2 Protein, GST-tagged	In Vitro Cell Free System	GST	469 amino acids	Inquiry
Mouse	ETS2-5348M	Recombinant Mouse ETS2 Protein	Mammalian Cell	His		Inquiry
Mouse	ETS2-2880M-B	Recombinant Mouse ETS2 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	ETS2-2880M	Recombinant Mouse ETS2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Zebrafish	ETS2-2948Z	Recombinant Zebrafish ETS2	Mammalian Cell	His		Inquiry
Chicken	ETS2-6864C	Recombinant Chicken ETS2	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
ETS2 Related Articles
ETS2 Related Research Area

ETS2 involved in several pathways and played different roles in them. We selected most pathways ETS2 participated on our site, such as Ras signaling pathway, Dorso-ventral axis formation, HTLV-I infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with ETS2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Ras signaling pathway	RHOA;MAPK10;RAP1A;PIK3R5;IGF1R;NF1;PLA2G10;FGF2;PGF
Dorso-ventral axis formation	KRAS;CPEB3;PPP1R2P9;MAPK1;FMN2;EGFRA;PIWIL1;GRB2;NOTCH4
HTLV-I infection	MYBL2;TRP53INP1;POLD1;MYBL1;DVL2;PPP3R2;TGFBR1;Adcy4;CCNB2

ETS2 has several biochemical functions, for example, DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding, glucocorticoid receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ETS2 itself. We selected most functions ETS2 had, and list some proteins which have the same functions with ETS2. You can find most of the proteins on our site.

Function	Related Protein
DNA binding	PAX2B;HES7;ZNF559;ZFP865;HMGB2;TCEA2;HER8.2;HOXD10A;ZFP507
RNA polymerase II core promoter proximal region sequence-specific DNA binding	HINFP;SREBF1;MEIS1;TFAP4;FOSB;ZNF253;ZKSCAN3;ZNF502;ETV6
glucocorticoid receptor binding	EP300;STAT3;NRIP1;FKBP4;ETS2;YWHAH;GRIP1;STAT5B;CEBPB
protein binding	FBXL15;LCA5;PAXIP1;MSI2;LGI1;CARD11;TNFAIP8L1;STAM2;ANKS4B
transcription factor activity, sequence-specific DNA binding	ARNTL1A;SCML1;TBX19;MNX1;NFIL3-3;FOXD1L;ZNF45;RFX3;TCF19
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding	EN1;ZNF217;FOXO1;OVOL1;HOXA2;NFIL3-5;BACH1;NKX6-2;CC2D1A

ETS2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ETS2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ETS2.

RFWD2; CDK10; TWIST1; TWIST2; RFWD2; ZFYVE9; sSL2; htrA; clpB; q7clb3_yerpe; proA; phnI; ubiG; gcvP; raf1_human_gene

Donnison, M; Broadhurst, R; et al. Elf5 and Ets2 maintain the mouse extraembryonic ectoderm in a dosage dependent synergistic manner. DEVELOPMENTAL BIOLOGY 397:77-88(2015).

Kim, JY; Lee, RH; et al. OVOL2 is a critical regulator of ER71/ETV2 in generating FLK1(+), hematopoietic, and endothelial cells from embryonic stem cells. BLOOD 124:2948-2952(2014).

Oncoprotein-Transcription Factors