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ETV2

Official Full Name

ets variant 2
Overview

ETV2 is a member of the ETS family of transcription factors. It has been proposed that ETV2 acts downstream of BMP, notch and wnt signalling in blood and vessel specification. ER71 has also shown to be important for Flk1 expression as well as hematopoietic and vascular development.
Synonyms

ETV2; ets variant 2; ER71; ETSRP71; ETS translocation variant 2; ets variant gene 2; ets-related protein 71;

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Zebrafish

Source

E.coli
HEK293
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	ETV2-283H	Recombinant Human ETV2 Protein, His-tagged	E.coli	His		Inquiry
Human	ETV2-932H	Recombinant Human ETV2	Mammalian Cell	His		Inquiry
Human	ETV2-3533H	Recombinant Human ETV2 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	ETV2-4366HF	Recombinant Full Length Human ETV2 Protein, GST-tagged	In Vitro Cell Free System	GST	342 amino acids	Inquiry
Human	ETV2-2887H	Recombinant Human ETV2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Human	ETV2-2887H-B	Recombinant Human ETV2 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	ETV2-5350M	Recombinant Mouse ETV2 Protein	Mammalian Cell	His		Inquiry
Mouse	ETV2-2881M-B	Recombinant Mouse ETV2 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	ETV2-2881M	Recombinant Mouse ETV2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Zebrafish	ETV2-3504Z	Recombinant Zebrafish ETV2	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
ETV2 Related Articles
ETV2 Related Research Area

ETV2 involved in several pathways and played different roles in them. We selected most pathways ETV2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ETV2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

ETV2 has several biochemical functions, for example, RNA polymerase II core promoter proximal region sequence-specific DNA binding, RNA polymerase II transcription factor activity, sequence-specific DNA binding, transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ETV2 itself. We selected most functions ETV2 had, and list some proteins which have the same functions with ETV2. You can find most of the proteins on our site.

Function	Related Protein
RNA polymerase II core promoter proximal region sequence-specific DNA binding	POU2F3;CHD7;SFPI1;FOSB;NEUROG3;JUNBB;TFAM;GCM1;RUNX2
RNA polymerase II transcription factor activity, sequence-specific DNA binding	MEF2D;ETV5B;GCM1;ETV6;FOXN1;OVOL1;BETA3;FOXO3B;TFDP1
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	EGR2;MAFB;POU3F2;SOX11;LEF1;PBX1;AKNA;HOXA5;TFAM

ETV2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ETV2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ETV2.

Morita, R; Suzuki, M; et al. ETS transcription factor ETV2 directly converts human fibroblasts into functional endothelial cells. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 112:160-165(2015).

Davis, JA; Desai, SP; et al. ETS Transcription Factor Etsrp/Etv2 Is Required for Lymphangiogenesis in Zebrafish and Is a Potential Therapeutic Target in Lymphatic Disease. BLOOD 124:-(2014).

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