Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953 Learn More

EXOSC2

Official Full Name

exosome component 2
Overview

Exosome component 2, also known as EXOSC2, is a protein which in humans is encoded by the EXOSC2 gene.
Synonyms

EXOSC2; exosome component 2; exosome complex component RRP4; homolog of yeast RRP4 (ribosomal RNA processing 4); 3 5 exoribonuclease (RRP4); hRrp4p; p7; RRP4; Rrp4p; Exosome complex exonuclease RRP4; Homolog of yeast RRP4 (ribosomal RNA processing 4), 3 5 exoribonuclease (RRP4); Homolog of yeast RRP4 (ribosomal RNA processing 4), 3-5-exoribonuclease; OTTHUMP00000022370; OTTHUMP00000022371; OTTHUMP00000022372; OTTHUMP00000022373; OTTHUMP00000022374; Ribosomal RNA processing protein 4; Ribosomal RNA- processing protein 4; ribosomal RNA-processing protein 4; homolog of yeast RRP4 (ribosomal RNA processing 4), 3-5-exori;

Type

Recombinant Proteins
Cell & Tissue Lysates

Species

Chicken
Human
Mouse
Zebrafish

Source

E.coli
HEK293
HEK293T
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
Strep
Myc
DDK
N/A
No tag

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	EXOSC2-12595H	Recombinant Human EXOSC2, His-tagged	E.coli	His	1-293a.a.	$319 / 25ug
Human	EXOSC2-3569H	Recombinant Human EXOSC2 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	EXOSC2-6503HCL	Recombinant Human EXOSC2 293 Cell Lysate	HEK293	N/A		Inquiry
Human	EXOSC2-4427HF	Recombinant Full Length Human EXOSC2 Protein, GST-tagged	In Vitro Cell Free System	GST	293 amino acids	Inquiry
Human	EXOSC2-0728H	Recombinant Human EXOSC2 Protein (M1-G293), His/Strep tagged	E.coli	His/Strep	M1-G293	Inquiry
Human	EXOSC2-0727H	Recombinant Human EXOSC2 Protein (M1-G293), Tag Free	E.coli	No tag	M1-G293	Inquiry
Mouse	Exosc2-2890M	Recombinant Mouse Exosc2 Protein, Myc/DDK-tagged	HEK293T	Myc/DDK		Inquiry
Zebrafish	EXOSC2-2351Z	Recombinant Zebrafish EXOSC2	Mammalian Cell	His		Inquiry
Chicken	EXOSC2-2026C	Recombinant Chicken EXOSC2	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
EXOSC2 Related Articles

EXOSC2 involved in several pathways and played different roles in them. We selected most pathways EXOSC2 participated on our site, such as RNA degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with EXOSC2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
RNA degradation	PAPD7;PFKMA;PAN3;PABPC1;PABPC1A;SKIV2L2;TOB1B;ENO3;TTC37

EXOSC2 has several biochemical functions, for example, 3-5-exoribonuclease activity, 7S RNA binding, NOT exoribonuclease activity. Some of the functions are cooperated with other proteins, some of the functions could acted by EXOSC2 itself. We selected most functions EXOSC2 had, and list some proteins which have the same functions with EXOSC2. You can find most of the proteins on our site.

Function	Related Protein
3-5-exoribonuclease activity	CNOT7;DIS3L2;EXOSC2;DIS3L;ERI1;EXOSC7;REXO2;ERI2;ERI3
7S RNA binding	SRP9;PIGC;SRP54A;EXOSC2;SRP72;SRP19;SRP68;SRP54;SRP14
NOT exoribonuclease activity	EXOSC5;EXOSC8;EXOSC1;EXOSC4;EXOSC3;EXOSC2;EXOSC7
protein binding	COPS6;AKAP5;RG9MTD1;OGT;EFCAB4B;CEP104;METTL9;OFCC1;PSMA7

EXOSC2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EXOSC2 here. Most of them are supplied by our site. Hope this information will be useful for your research of EXOSC2.

EXOSC3; EXOSC4; EXOSC10; EXOSC9

Jaworski, E; Narayanan, A; et al. Human T-lymphotropic Virus Type 1-infected Cells Secrete Exosomes That Contain Tax Protein. JOURNAL OF BIOLOGICAL CHEMISTRY 289:22284-22305(2014).

Hau, HH; Walsh, RJ; et al. Tristetraprolin recruits functional mRNA decay complexes to ARE sequences. JOURNAL OF CELLULAR BIOCHEMISTRY 100:1477-1492(2007).