EYA2
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Official Full Name
eyes absent homolog 2
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Overview
This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may be post-translationally;modified and may play a role in eye development. A similar protein in mice can act as a transcriptional activator.;Alternative splicing results in multiple transcript variants, but the full-length natures of all of these variants;have not yet been determined. -
Synonyms
EYA2; eyes absent homolog 2 (Drosophila); eyes absent (Drosophila) homolog 2; eyes absent homolog 2; EAB1; MGC10614;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Zebrafish
- E.coli
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- SUMO
- N/A
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | EYA2-18H | Recombinant Human EYA2 protein, His-tagged | E.coli | His |
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| Human | EYA2-3592H | Recombinant Human EYA2 Protein, GST-tagged | Wheat Germ | GST |
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| Human | EYA2-6491HCL | Recombinant Human EYA2 293 Cell Lysate | HEK293 | N/A |
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| Human | EYA2-2876H | Recombinant Human EYA2 protein, His-SUMO-tagged | E.coli | His-SUMO | 1-514aa |
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| Human | EYA2-4457HF | Recombinant Full Length Human EYA2 Protein, GST-tagged | In Vitro Cell Free System | GST | 538 amino acids |
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| Human | EYA2-3101H | Recombinant Human EYA2 protein, His-tagged | E.coli | His | 241-583 aa | |
| Mouse | EYA2-5397M | Recombinant Mouse EYA2 Protein | Mammalian Cell | His |
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| Mouse | EYA2-2910M | Recombinant Mouse EYA2 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Mouse | EYA2-2910M-B | Recombinant Mouse EYA2 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Zebrafish | EYA2-1281Z | Recombinant Zebrafish EYA2 | Mammalian Cell | His |
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| Chicken | EYA2-6477C | Recombinant Chicken EYA2 | Mammalian Cell | His |
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- Involved Pathway
- Protein Function
- Interacting Protein
- EYA2 Related Articles
EYA2 involved in several pathways and played different roles in them. We selected most pathways EYA2 participated on our site, such as DNA Double Strand Break Response, DNA Double-Strand Break Repair, DNA Repair, which may be useful for your reference. Also, other proteins which involved in the same pathway with EYA2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| DNA Double Strand Break Response | UIMC1;RAD50;BAZ1B;KDM4A;TP53BP1;CHEK2;EYA2;BRE;RNF168 |
| DNA Double-Strand Break Repair | RBBP8;RAD17;GEN1;RAD9A;RAD9;PPP4CB;BAZ1B;PPP4R2A;PARP2 |
| DNA Repair | CHEK2;FUZ;RAD9A;DDB2;PPP4CA;COPS7A;USP43A;ZFP830;YY1 |
| Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks | EYA3;KDM4B;BAZ1B;EYA4;KDM4A;EYA2 |
EYA2 has several biochemical functions, for example, magnesium ion binding, protein binding, protein tyrosine phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by EYA2 itself. We selected most functions EYA2 had, and list some proteins which have the same functions with EYA2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| magnesium ion binding | PRPS1A;NT5C1AA;NCS1;NT5C3B;CIB3;IMPA1;HPGDS;ENDOV;OPA1 |
| protein binding | C5orf20;CST5;MC3R;DYRK2;ANKS4B;HOXB9;RARRES2;LRFN4;NCK2 |
| protein tyrosine phosphatase activity | PTPRO;PALD1A;DNAJC6;TIMM50;PTPN14;DUSP22A;MTM1;PTPN11B;DUSP26 |
EYA2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EYA2 here. Most of them are supplied by our site. Hope this information will be useful for your research of EYA2.
TFAP2A; SIX1; TFAP2C; RBPMS
- Q&As
- Reviews
Q&As (5)
Ask a questionTargeting EYA2 protein could have therapeutic potential in cancer treatment, either by inhibiting its function or modulating its activity.
EYA2 protein is involved in regulating the cell cycle and promoting cell proliferation, which has implications for cancer development and progression.
EYA2 protein has been linked to drug resistance in cancer cells, making it an important factor to consider in developing effective treatment strategies.
EYA2 protein has been shown to influence cell differentiation processes, potentially impacting tissue development and regeneration.
EYA2 protein has been shown to interact with DNA repair proteins, influencing the efficiency of DNA repair processes.
Customer Reviews (3)
Write a reviewI am confident that the EYA2 protein will unravel crucial insights into molecular mechanisms, greatly enhancing the significance and impact of my scientific investigations.
the manufacturer's commitment to providing excellent technical support adds an additional layer of confidence to my choice of the EYA2 protein.
By relying on the EYA2 protein, I can approach my research with unwavering confidence in its quality and the unparalleled support extended by its manufacturer.
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