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ECE1

  • Official Full Name

    endothelin converting enzyme 1

  • Overview

    The protein encoded by this gene is involved in proteolytic processing of endothelin precursors to biologically active peptides. Mutations in this gene are associated with Hirschsprung disease, cardiac defects and autonomic dysfunction. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Sep 2009]
  • Synonyms

    ECE1; endothelin converting enzyme 1; ECE; endothelin-converting enzyme 1; ECE-1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Bos taurus (Bovine)
  • Cavia porcellus (Guinea pig)
  • Chicken
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Rat
  • Rattus norvegicus (Rat)
  • Zebrafish
  • CHO
  • E.coli
  • E.coli expression system
  • HEK293
  • HEK293T
  • Human Cell
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His|T7
  • Myc
  • DDK
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ECE1-3027H Recombinant Human ECE1 Protein, GST-tagged Wheat Germ GST
Human ECE1-3858H Recombinant Human ECE1 protein, His-tagged HEK293 His Gln90-Trp770
Human ECE1-2687H Recombinant Human ECE1 protein, His & T7-tagged E.coli His/T7 Leu469~Glu721 (Accession # P42892)
Human ECE1-2023HCL Recombinant Human ECE1 cell lysate Human Cell N/A
Human ECE1-4150HF Recombinant Full Length Human ECE1 Protein, GST-tagged In Vitro Cell Free System GST 770 amino acids
Human ECE1-926H Recombinant Human ECE1 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human ECE1-3668H Recombinant Human ECE1 protein, His-tagged E.coli His 90-189 aa
Human ECE1-445H Recombinant Human ECE1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human ECE1-1885H Recombinant Human ECE1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human ECE1-2703H Recombinant Human ECE1 protein, His-tagged E.coli His 335-425 aa
Human ECE1-2021H Recombinant Human ECE1 Protein (Leu469-Glu721), N-His tagged E.coli N-His Leu469-Glu721
Mouse Ece1-422M Active Recombinant Mouse Endothelin Converting Enzyme 1, His-tagged CHO His
Mouse Ece1-38M Recombinant Mouse Ece1 protein, His-tagged E.coli His
Mouse Ece1-2715M Recombinant Mouse Ece1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat Ece1-2688R Recombinant Rat Ece1 protein, His & T7-tagged E.coli His/T7 His214~Ala448 (Accession # P42893)
Bos taurus (Bovine) RFL32993BF Recombinant Full Length Bovine Endothelin-Converting Enzyme 1(Ece1) Protein, His-Tagged E.coli expression system His Full Length (1-754)
Cavia porcellus (Guinea pig) RFL33931CF Recombinant Full Length Guinea Pig Endothelin-Converting Enzyme 1(Ece1) Protein, His-Tagged E.coli expression system His Full Length (1-754)
Homo sapiens (Human) RFL30038HF Recombinant Full Length Human Endothelin-Converting Enzyme 1(Ece1) Protein, His-Tagged E.coli expression system His Full Length (1-770)
Rattus norvegicus (Rat) RFL6774RF Recombinant Full Length Rat Endothelin-Converting Enzyme 1(Ece1) Protein, His-Tagged E.coli expression system His Full Length (1-762)
Zebrafish ECE1-4866Z Recombinant Zebrafish ECE1 Mammalian Cell His
Chicken ECE1-6282C Recombinant Chicken ECE1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • ECE1 Related Research Area

ECE1 involved in several pathways and played different roles in them. We selected most pathways ECE1 participated on our site, such as Corticotropin-releasing hormone, Endothelin, SIDS Susceptibility Pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with ECE1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Corticotropin-releasing hormoneECE1;CRHR2;TRIM28;TFAP2A;CRHR1;KRT1;TCF4;CYP11A1;JUND
EndothelinEDNRB;MYL1;CALCRL;EDN1;EDNRA;RAMP1;ECE1;CALCA;CNN1
SIDS Susceptibility PathwaysLMX1B;RUNX3;PHOX2B;TPPP;KCNJ8;EN1;KCNH2;POU3F2;CTCF

ECE1 has several biochemical functions, for example, endopeptidase activity, metal ion binding, metalloendopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ECE1 itself. We selected most functions ECE1 had, and list some proteins which have the same functions with ECE1. You can find most of the proteins on our site.

Function Related Protein
endopeptidase activityHTRA4;NCSTN;TRAPPC12;PSMA7;PSMA6;PSMB4;ADAMTS3;PSMB2;SENP5
metal ion bindingNEURL1B;KDM8;POLI;GNAT3;ZNF281B;NDUFS8;EXT1C;FDX1B;HE1A
metalloendopeptidase activityMMP9;ADAMTS10;ZMPSTE24;SPG7;ADAM15;MMP30;ADAMDEC1;UQCRC2B;ADAM22
peptide hormone bindingNPR3;ANXA5;RXFP2;PTH1R;GALR3;GALR1;OXTR;AGTR1A;AGTR2
protein bindingRNF182;KLRC2;CCL11;PRNP;GNB2L1;ITGB3BP;NFE2L1;FAM76B;HIST1H2AG
protein homodimerization activityALDH1A3;PTPRE;DMRT3;BAXB;PPP2R4;PDE2A;CD4;CADM3;MYOM1

ECE1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ECE1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ECE1.

CLK2; KRTAP10-5; yhjW; dmsB; cona_canen

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