FAH
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Official Full Name
fumarylacetoacetate hydrolase (fumarylacetoacetase)
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Overview
This gene encodes the last enzyme in the tyrosine catabolism pathway. FAH deficiency is associated with Type 1 hereditary tyrosinemia (HT). -
Synonyms
FAH; fumarylacetoacetate hydrolase (fumarylacetoacetase); fumarylacetoacetase; FAA; beta-diketonase; FLJ51912;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Rat
- Rhesus Macaque
- Zebrafish
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mamanlian cells
- Mammalian Cell
- Mammalian cells
- Wheat Germ
- C
- His
- Flag
- GST
- His (Fc)
- Avi
- Myc
- DDK
- MYC
- Myc|DDK
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
- FAH Related Articles
FAH involved in several pathways and played different roles in them. We selected most pathways FAH participated on our site, such as Tyrosine metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with FAH were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Tyrosine metabolism | HPDB;MIF;ADH2-1;TAT;ALDH3A1;GOT2;AOX2P;ADH2-2;TYRP1 |
| Metabolic pathways | SCP2A;TYMS;EXT1B;ENO3;GM5506;GATB;ATP5IA;G6PCA.1;UOX |
FAH has several biochemical functions, for example, fumarylacetoacetase activity, metal ion binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FAH itself. We selected most functions FAH had, and list some proteins which have the same functions with FAH. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| fumarylacetoacetase activity | |
| metal ion binding | SIAH1A;ATF7A;GTF3A;ADH8A;STAMBPA;PCXA;ZNF234;ZNF395A;ZFP652 |
| protein binding | SMAD7;ATP5O;ALDH7A1;CCDC60;HELZ2;TIPIN;RIN1;PAK4;SYTL2 |
FAH has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FAH here. Most of them are supplied by our site. Hope this information will be useful for your research of FAH.
TCF4; KRTAP5-9; KRTAP10-8; SERTAD1; ADAMTSL4; EGFR
- Q&As
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