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FARSB

Official Full Name

phenylalanyl-tRNA synthetase, beta subunit
Overview

This gene encodes a highly conserved enzyme that belongs to the aminoacyl-tRNA synthetase class IIc subfamily. This enzyme comprises the regulatory beta subunits that form a tetramer with two catalytic alpha subunits. In the presence of ATP, this tetramer is responsible for attaching L-phenylalanine to the terminal adenosine of the appropriate tRNA. A pseudogene located on chromosome 10 has been identified. This gene encodes a highly conserved enzyme that belongs to the aminoacyl-tRNA synthetase class IIc subfamily. This enzyme comprises the regulatory beta subunits that form a tetramer with two catalytic alpha subunits. In the presence of ATP, this tetramer
Synonyms

FARSB; phenylalanyl-tRNA synthetase, beta subunit; FARSLB, phenylalanyl tRNA synthetase like, beta subunit; phenylalanine--tRNA ligase beta subunit; FRSB; PheHB; phenylalanine tRNA ligase 1; beta; cytoplasmic; phenylalanine-tRNA ligase beta chain; phenyl; PheRS; FARSLB; HSPC173; phenylalanyl-tRNA synthetase beta chain; OTTHUMP00000164205; phenylalanine--tRNA ligase beta chain; phenylalanyl-tRNA synthetase beta-subunit; phenylalanine tRNA ligase 1, beta, cytoplasmic; phenylalanyl-tRNA synthetase-like, beta subunit; phenylalanine-tRNA synthetase-like, beta subunit;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Mouse
Zebrafish

Source

E.coli
HEK293
HEK293T
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
Myc
DDK
N/A
N

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	FARSB-12750H	Recombinant Human FARSB, His-tagged	E.coli	His	240-589a.a.	$319 / 25ug
Human	FARSB-3848H	Recombinant Human FARSB Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	FARSB-6325HCL	Recombinant Human FARSB 293 Cell Lysate	HEK293	N/A		Inquiry
Human	FARSB-3392H	Recombinant Human FARSB Protein (Met1-Leu589), N-His tagged	E.coli	N-His	Met1-Leu589	Inquiry
Human	FARSB-4086H	Recombinant Human FARSB Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK		Inquiry
Human	FARSB-1461H	Recombinant Human FARSB Protein, His-tagged	E.coli	N-His	Met1-Val289	Inquiry
Human	FARSB-4771HF	Recombinant Full Length Human FARSB Protein, GST-tagged	In Vitro Cell Free System	GST	589 amino acids	Inquiry
Mouse	FARSB-5684M	Recombinant Mouse FARSB Protein	Mammalian Cell	His		Inquiry
Mouse	FARSB-3120M	Recombinant Mouse FARSB Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	Farsb-2956M	Recombinant Mouse Farsb Protein, Myc/DDK-tagged	HEK293T	Myc/DDK		Inquiry
Mouse	FARSB-3120M-B	Recombinant Mouse FARSB Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	Farsb-1462M	Recombinant Mouse Farsb Protein, His-tagged	E.coli	N-His	Met1-Val222	Inquiry
Zebrafish	FARSB-1844Z	Recombinant Zebrafish FARSB	Mammalian Cell	His		Inquiry
Chicken	FARSB-1681C	Recombinant Chicken FARSB	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
FARSB Related Articles

FARSB involved in several pathways and played different roles in them. We selected most pathways FARSB participated on our site, such as Aminoacyl-tRNA biosynthesis, Cytosolic tRNA aminoacylation, Gene Expression, which may be useful for your reference. Also, other proteins which involved in the same pathway with FARSB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Aminoacyl-tRNA biosynthesis	FARS2;NARS;NARS2;TARS2;SEPSECS;PARS2;GATC;GARS;SARS
Cytosolic tRNA aminoacylation	EEF1E1;AIMP2;MADD;AIMP1;DARS;AARS;FARSB;KARS
Gene Expression	ESR2B;SESN3;NRBF2;ZNF498;ZNF75D;ZNF2;TRMT11;TBX5;ZNF563
tRNA Aminoacylation	WARS2;EARS2;KARS;FARS2;MADD;EEF1E1;FARSB;AARS;DARS

FARSB has several biochemical functions, for example, ATP binding, RNA binding, magnesium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FARSB itself. We selected most functions FARSB had, and list some proteins which have the same functions with FARSB. You can find most of the proteins on our site.

Function	Related Protein
ATP binding	DTYMK;TAOK2;TUT1;DCKL1B;MKKS;ATP1A1A.3;FAM20C;CHEK2;HSPA9
RNA binding	KHDRBS1B;RPL7A;SMN2;ZFP346;SRRM4;TROVE2;RPLP0;ZRANB2;SETD1BA
magnesium ion binding	PPA1B;TDP2B;RRAGC;PIF1;ABL2;ERN2;PGM2;IRAK4;ATP8B1
phenylalanine-tRNA ligase activity	FDXACB1;FARS2;FARSB;FARSA

FARSB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FARSB here. Most of them are supplied by our site. Hope this information will be useful for your research of FARSB.

VCAM1; ACTB; DDA1; FN1; EIF2AK2; HDGF; SLX4

Carr, JF; Danziger, ME; et al. Engineering the Genome of Thermus thermophilus Using a Counterselectable Marker. JOURNAL OF BACTERIOLOGY 197:1135-1144(2015).

Mermershtain, I; Finarov, I; et al. Idiosyncrasy and identity in the prokaryotic phe-system: Crystal structure of E-coli phenylalanyl-tRNA synthetase complexed with phenylalanine and AMP. PROTEIN SCIENCE 20:160-167(2011).