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FBLN2

  • Official Full Name

    fibulin 2

  • Overview

    This gene encodes an extracellular matrix protein, which belongs to the fibulin family. This protein binds various extracellular ligands and calcium. It may play a role during organ development, in particular, during the differentiation of heart, skeletal and neuronal structures. Alternatively spliced transcript variants encoding different isoforms have been identified.
  • Synonyms

    FBLN2; fibulin 2; fibulin-2; FBLN2_HUMAN; FIBL-2; OTTHUMP00000216670; OTTHUMP00000216671; OTTHUMP00000216672;

  • Recombinant Proteins
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Wheat Germ
  • GST
  • HA
  • His
  • N/A
  • N
  • T7|His
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human FBLN2-01H Active Recombinant Human FBLN2 protein, HA-tagged HEK293 HA
Human FBLN2-198H Recombinant Human FBLN2 protein, T7/His-tagged E.coli T7/His
Human FBLN2-3874H Recombinant Human FBLN2 Protein, GST-tagged Wheat Germ GST
Human FBLN2-28902TH Recombinant Human FBLN2 Wheat Germ N/A 109 amino acids
Human FBLN2-4882HF Recombinant Full Length Human FBLN2 Protein, GST-tagged In Vitro Cell Free System GST 28-1184 amino acids
Human FBLN2-2600H Recombinant Human FBLN2 Protein (Asp858-Leu1184), N-His tagged E.coli N-His Asp858-Leu1184
Human FBLN2-159H Recombinant Human FBLN2 Protein, His-tagged E.coli His Ile858~Ser1069
Mouse Fbln2-7896M Recombinant Mouse Fbln2 protein, His-tagged E.coli His Val896~Glu1106
Rat Fbln2-7897R Recombinant Rat Fbln2 protein, His-tagged E.coli His Asp1013~Pro1221 (Accession # G3V6X1)
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • FBLN2 Related Research Area

FBLN2 involved in several pathways and played different roles in them. We selected most pathways FBLN2 participated on our site, such as Elastic fibre formation, Extracellular matrix organization, Molecules associated with elastic fibres, which may be useful for your reference. Also, other proteins which involved in the same pathway with FBLN2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Elastic fibre formationLOXL2;BMP10;FBN2;MFAP3;MFAP5;MFAP1;FBN1;LTBP4;LOX
Extracellular matrix organizationMFAP4;TLL1;MMP12;F11R.2;MGC174155;LOXL3;HAPLN1;MMP15;PCOLCE
Molecules associated with elastic fibresFBLN1;MFAP1B;MFAP2;MFAP5;LTBP3;LTBP4;LTBP2;EFEMP2;MFAP1

FBLN2 has several biochemical functions, for example, calcium ion binding, extracellular matrix binding, extracellular matrix structural constituent. Some of the functions are cooperated with other proteins, some of the functions could acted by FBLN2 itself. We selected most functions FBLN2 had, and list some proteins which have the same functions with FBLN2. You can find most of the proteins on our site.

Function Related Protein
calcium ion bindingMGMT;CDH10;SYTL1;DAG1;MYL2B;THBD;ITSN1;CETN4;CRB2B
extracellular matrix bindingSID4;BGN;GPR56;CD248;SPOCK2;DMP1;CYR61;TGFBI;ITGAV
extracellular matrix structural constituentCOL27A1;ELN;COL1A1B;COMP;COL11A1B;TFPI2;COL27A1B;COL4A6;COL5A3B

FBLN2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FBLN2 here. Most of them are supplied by our site. Hope this information will be useful for your research of FBLN2.

ATN1; ZYX; htrA; mnmG; TFAP2C; q9wmx2-pro_0000037541; q9wmx2-pro_0000037546; q9wmx2-pro_0000037548

  • Q&As
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