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FBXL12

  • Official Full Name

    F-box and leucine-rich repeat protein 12

  • Overview

    Members of the F-box protein family, such as FBXL12, are characterized by an approximately 40-amino acid F-box motif.;SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as;protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination;targets through other protein interaction domains (Jin et al., 2004 (PubMed 15520277)).
  • Synonyms

    FBXL12; F-box and leucine-rich repeat protein 12; F-box/LRR-repeat protein 12; Fbl12; FLJ20188; F box and leucine rich repeat protein 12; F box protein FBL12; F box/LRR repeat protein 12; FBXL 12; F-box protein FBL12;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human FBXL12-3887H Recombinant Human FBXL12 Protein, GST-tagged Wheat Germ GST
Human FBXL12-6314HCL Recombinant Human FBXL12 293 Cell Lysate HEK293 N/A
Human FBXL12-577H Recombinant Human FBXL12 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human FBXL12-2965H Recombinant Human FBXL12 protein, His-tagged E.coli His 170-326 aa
Human FBXL12-4921HF Recombinant Full Length Human FBXL12 Protein, GST-tagged In Vitro Cell Free System GST 326 amino acids
Mouse FBXL12-5711M Recombinant Mouse FBXL12 Protein Mammalian Cell His
Mouse FBXL12-3139M-B Recombinant Mouse FBXL12 Protein Pre-coupled Magnetic Beads HEK293
Mouse Fbxl12-2960M Recombinant Mouse Fbxl12 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse FBXL12-3139M Recombinant Mouse FBXL12 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Chicken FBXL12-7033C Recombinant Chicken FBXL12 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

FBXL12 involved in several pathways and played different roles in them. We selected most pathways FBXL12 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with FBXL12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

FBXL12 has several biochemical functions, for example, protein binding, contributes_to ubiquitin protein ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by FBXL12 itself. We selected most functions FBXL12 had, and list some proteins which have the same functions with FBXL12. You can find most of the proteins on our site.

Function Related Protein
protein bindingAPOA1;UBAP1;PLCG1;MAPKAPK3;ERCC3;PLD1;APPB;RPUSD3;TNIP1
contributes_to ubiquitin protein ligase activityFBXL14;FBXL20;UBXN6;CUL4B;MED11;CUL1A;FBXL22;FBXL15;CUL1B

FBXL12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FBXL12 here. Most of them are supplied by our site. Hope this information will be useful for your research of FBXL12.

DOCK8; LNX1; RNF32; CDKN1C; HSP90AB1; PSEN2; FXYD3; CDC37; MAST1; RBX1

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