Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953 Learn More

FBXL4

Official Full Name

F-box and leucine-rich repeat protein 4
Overview

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains at least 9 tandem leucine-rich repeats.
Synonyms

FBXL4; F-box and leucine-rich repeat protein 4; F-box/LRR-repeat protein 4; FBL4; FBL5; F box and leucine rich repeat protein 4; F box protein FBL4/FBL5; F box/LRR repeat protein 4; F-box protein FBL 4; F-box protein FBL4/FBL5; FBL 4; FBL 5; FBXL4_HUMAN; F-box protein FBL4; OTTHUMP00000016888;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Rhesus Macaque
Zebrafish

Source

HEK293
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	FBXL4-3905H	Recombinant Human FBXL4 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	FBXL4-600HCL	Recombinant Human FBXL4 cell lysate		N/A		Inquiry
Human	FBXL4-4999HF	Recombinant Full Length Human FBXL4 Protein, GST-tagged	In Vitro Cell Free System	GST	621 amino acids	Inquiry
Mouse	FBXL4-5724M	Recombinant Mouse FBXL4 Protein	Mammalian Cell	His		Inquiry
Mouse	FBXL4-3148M	Recombinant Mouse FBXL4 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	FBXL4-3148M-B	Recombinant Mouse FBXL4 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rhesus Macaque	FBXL4-1655R	Recombinant Rhesus monkey FBXL4 Protein, His-tagged	Mammalian Cell	His		Inquiry
Rhesus Macaque	FBXL4-1479R-B	Recombinant Rhesus Macaque FBXL4 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rhesus Macaque	FBXL4-1479R	Recombinant Rhesus Macaque FBXL4 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Zebrafish	FBXL4-1707Z	Recombinant Zebrafish FBXL4	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

FBXL4 involved in several pathways and played different roles in them. We selected most pathways FBXL4 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with FBXL4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

FBXL4 has several biochemical functions, for example, contributes_to ubiquitin protein ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by FBXL4 itself. We selected most functions FBXL4 had, and list some proteins which have the same functions with FBXL4. You can find most of the proteins on our site.

Function	Related Protein
contributes_to ubiquitin protein ligase activity	C10orf46;FBXL22;CUL2;CUL5A;CUL1;FBXL14;FBXL14A;FBXL3B;FBXL6

FBXL4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FBXL4 here. Most of them are supplied by our site. Hope this information will be useful for your research of FBXL4.

nrdD; Tpx2; Nedd1; EXOSC2