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FBXO21

Official Full Name

F-box protein 21
Overview

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternative splicing of this gene generates 2 transcript variants.
Synonyms

FBXO21; F-box protein 21; F box only protein 21; F-box only protein 21; FBX21; KIAA0875; F box protein 21; FBX21_HUMAN;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse

Source

HEK293
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	FBXO21-3920H	Recombinant Human FBXO21 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	FBXO21-6305HCL	Recombinant Human FBXO21 293 Cell Lysate	HEK293	N/A		Inquiry
Human	FBXO21-5025HF	Recombinant Full Length Human FBXO21 Protein, GST-tagged	In Vitro Cell Free System	GST	621 amino acids	Inquiry
Mouse	FBXO21-5735M	Recombinant Mouse FBXO21 Protein	Mammalian Cell	His		Inquiry
Mouse	FBXO21-3153M-B	Recombinant Mouse FBXO21 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	FBXO21-3153M	Recombinant Mouse FBXO21 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry

Involved Pathway
Protein Function
Interacting Protein

FBXO21 involved in several pathways and played different roles in them. We selected most pathways FBXO21 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with FBXO21 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

FBXO21 has several biochemical functions, for example, DNA binding, ubiquitin-protein transferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by FBXO21 itself. We selected most functions FBXO21 had, and list some proteins which have the same functions with FBXO21. You can find most of the proteins on our site.

Function	Related Protein
DNA binding	ZNF625;DLX4B;ZNF443;ZNF292A;TSN;DEK;ERCC6L;PHC3;CEBPG
ubiquitin-protein transferase activity	RNF11;LTN1;TRIM36;SIAH2L;UBE2D2A;LNX1;UBE2C;RNF141;TRIM5

FBXO21 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FBXO21 here. Most of them are supplied by our site. Hope this information will be useful for your research of FBXO21.

CNTNAP4