fbxo32
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  • Official Full Name
  • F-box protein 32
  • Background
  • This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms.
  • Synonyms
  • FBXO32; F-box protein 32; F box only protein 32; F-box only protein 32; ATROGIN1; Fbx32; MAFbx; 4833442G10Rik; AI430017; Atrogin 1; Atrogin-1; Atrophy gene 1; FBX32_HUMAN; fbxo25; FLJ32424; MGC108443; MGC137646; MGC33610; Muscle atrophy F box; Muscle atrophy F box protein; Muscle atrophy F-box protein
Cat.#:FBXO32-3936HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human FBXO32 Protein, GST-tagged
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Cat.#:FBXO32-12796HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human FBXO32, GST-tagged
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Cat.#:FBXO32-22HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human FBXO32 protein, His-tagged
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Cat.#:FBXO32-28812THTag:
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human FBXO32
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Cat.#:FBXO32-5744MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse FBXO32 Protein
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Cat.#:FBXO32-2295RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat FBXO32 Protein
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Cat.#:FBXO32-1663RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey FBXO32 Protein, His-tagged
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Cat.#:FBXO32-2644CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken FBXO32
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Cat.#:FBXO32-11158ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish FBXO32
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Cat.#:FBXO32-6297HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human FBXO32 293 Cell Lysate
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FBXO32 Related Articles

Ma, L; Shen, CA; et al. EXTRACELLULAR SIGNAL-REGULATED KINASE-MAMMALIAN TARGET OF RAPAMYCIN SIGNALING AND FORKHEAD-BOX TRANSCRIPTION FACTOR 3A PHOSPHORYLATION ARE INVOLVED IN TESTOSTERONE'S EFFECT ON SEVERE BURN INJURY IN A RAT MODEL. SHOCK 43:85-91(2015).
Cappelletti, C; Galbardi, B; et al. Autophagy, Inflammation and Innate Immunity in Inflammatory Myopathies. PLOS ONE 9:-(2014).