Background
Members of the F-box protein family, such as FBXW12, are characterized by an approximately 40-amino acid F-box motif.;SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603034), and F-box proteins, act as;protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination;targets through other protein interaction domains (Jin et al., 2004 (PubMed 15520277)).
Synonyms
FBXW12; F-box and WD repeat domain containing 12; F box and WD 40 domain protein 12 , F box only protein 35 , FBXO35; F-box/WD repeat-containing protein 12; Fbw12; F-box only protein 35; F-box and WD-40 domain protein 12; F-box- and WD40-repeat-containing protein; F-box and WD-40 domain-containing protein 12; FBXO12; FBXO35; MGC120385; MGC120386; MGC120387