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FCER1A

  • Official Full Name

    Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide

  • Overview

    Binds to the Fc region of immunoglobulins epsilon. High affinity receptor. Responsible for initiating the allergic response. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines.
  • Synonyms

    FCER1A; Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide; FCE1A; high affinity immunoglobulin epsilon receptor subunit alpha; Fc-epsilon RI-alpha; Fc epsilon RI alpha-chain; igE Fc receptor subunit alpha; Fc IgE receptor, alpha polypep;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Cynomolgus
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Rat
  • Rattus norvegicus (Rat)
  • E.coli
  • E.coli expression system
  • HEK293
  • Human Cell
  • In Vitro Cell Free System
  • In vitro E. coli expression system
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Yeast
  • C
  • hFc
  • His
  • Fc
  • GST
  • His (Fc)
  • Avi
  • His|SUMO
  • SUMO
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human FCER1A-725H Active Recombinant Human FCER1A, His-tagged Mammalian cells His
Human FCER1A-338H Recombinant Human FCER1A Protein(Val26-Gln205), His-tagged HEK293 C-His Val26-Gln205
Human FCER1A-193H Active Recombinant Human FCER1A, His-tagged, Biotinylated HEK293 His Val 26 - Gln 205
Human FCER1A-1460H Active Recombinant Human FCER1A protein, Fc-tagged HEK293 Fc Val26-Leu204
Human FCER1A-311H Recombinant Human Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide, His-tagged E.coli His
Human FCER1A-1209H Recombinant Human FCER1A Protein, His-SUMO-tagged E.coli His/SUMO
Human FCER1A-8563H Recombinant Human FCER1A protein(Met1-Gln205), His-tagged HEK293 C-His Met1-Gln205
Human FCER1A-237H Recombinant Human FCER1A Mammalian Cell His
Human FCER1A-204H Recombinant Human FCER1A, His-tagged HEK293 His
Human FCER1A-28166TH Recombinant Human FCER1A, GST-tagged Wheat Germ GST
Human FCER1A-1394HCL Recombinant Human FCER1A cell lysate Human Cell N/A
Human FCER1A-6928HF Recombinant Full Length Human FCER1A Protein, GST-tagged In Vitro Cell Free System GST 257 amino acids
Human FCER1A-567H Recombinant Human FCER1A Protein (Met1-Gln205) HEK293 N/A Met1-Gln205
Human FCER1A-245H Recombinant Human FCER1A Protein, His-tagged HEK293 His 257
Human FCER1A-2929H Recombinant Human FCER1A Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human FCER1A-2929H-B Recombinant Human FCER1A Protein Pre-coupled Magnetic Beads HEK293
Human FCER1A-25H Active Recombinant Human FCER1A Protein (26-205aa), C-His tagged HEK293 C-His 26-205 aa
Human FCER1A-2099H Recombinant Human FCER1A Protein (26-205 aa), His-tagged Yeast His 26-205 aa
Mouse Fcer1a-8688M Recombinant Mouse Fcer1a protein(Met1-Gln204), hFc-tagged HEK293 C-hFc Met1-Gln204
Mouse FCER1A-1389MCL Recombinant Mouse FCER1A cell lysate Human Cell N/A
Mouse Fcer1a-1472M Recombinant Mouse Fcer1a Protein, His-tagged E.coli N-His Ala24-Gln204
Mouse FCER1A-2710M Recombinant Mouse FCER1A Full Length Transmembrane protein (24-250 aa), His-SUMO-tagged In vitro E. coli expression system His-SUMO 24-250aa
Mouse Fcer1a-2376M Recombinant Mouse Fcer1a protein, His-SUMO-tagged E.coli His-SUMO 24-250aa
Rat FCER1A-2304R Recombinant Rat FCER1A Protein Mammalian Cell His
Rat FCER1A-1961R-B Recombinant Rat FCER1A Protein Pre-coupled Magnetic Beads HEK293
Rat FCER1A-1961R Recombinant Rat FCER1A Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Cynomolgus FCER1A-1459C Active Recombinant Cynomolgus FCER1A protein, Fc-tagged HEK293 Fc Val29-Lys204
Cynomolgus FCER1A-1458C Active Recombinant Cynomolgus FCER1A protein, His-tagged HEK293 His Val29-Lys204
Mus musculus (Mouse) RFL29863MF Recombinant Full Length Mouse High Affinity Immunoglobulin Epsilon Receptor Subunit Alpha(Fcer1A) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (24-250aa)
Rattus norvegicus (Rat) RFL15030RF Recombinant Full Length Rat High Affinity Immunoglobulin Epsilon Receptor Subunit Alpha(Fcer1A) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (24-245)
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • FCER1A Related Research Area

FCER1A involved in several pathways and played different roles in them. We selected most pathways FCER1A participated on our site, such as Sphingolipid signaling pathway, Phospholipase D signaling pathway, Fc epsilon RI signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with FCER1A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Sphingolipid signaling pathwayBCL2;PIK3R3;RAC3;NFKB1;PLCB2;PRKCB;PPP2R3A;BDKRB2;PIK3R1
Phospholipase D signaling pathwayLPAR2;AGPAT5;SHC4;AVPR1A;HRAS;PLCB4;PIK3CG;GAB1;AKT1
Fc epsilon RI signaling pathwayIL4;LYN;IL5;FYN;TNF;MAPK3;PLA2G4D;AKT2;MAP2K4
AsthmaH2-AB1;HLA-DRB5;HLA-DQA2;RNASE3;FCER1A;CCL11;IL9;IL10;HLA-DQB1

FCER1A has several biochemical functions, for example, IgE binding, IgE receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by FCER1A itself. We selected most functions FCER1A had, and list some proteins which have the same functions with FCER1A. You can find most of the proteins on our site.

Function Related Protein
IgE bindingFCER1G;Fcer2a;FCER2;CD247L;MS4A2;FCER1A;LGALS3
IgE receptor activityMS4A2;FCER1G;CD247L;FCER1A

FCER1A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FCER1A here. Most of them are supplied by our site. Hope this information will be useful for your research of FCER1A.

PDHB

  • Q&As
  • Reviews

Q&As (6)

Ask a question
Is FCER1A expression regulated? 09/28/2022

Modulation of FCER1A expression can be achieved through techniques such as gene knockout, gene silencing, or gene transduction. In addition, its expression levels can also be affected by altering environmental factors such as nutrition, inflammation, etc.

How can I detect the expression level of FCER1A? 07/25/2022

The expression level of FCER1A can be detected by gene expression profiling or immunohistochemistry.

Is there a role for FCER1A in the immune system? 11/03/2021

FCER1A plays a key role in the immune system, recognizing and presenting antigens to T cell receptors, thereby initiating an adaptive immune response.

What diseases is FCER1A associated with? 09/30/2021

Studies have shown that FCER1A is associated with the risk of some autoimmune diseases, inflammatory diseases, and certain cancers.

What is the significance of studying FCER1A? 09/28/2021

Studying FCER1A can help to gain insight into the mechanisms of immune response and inflammatory response, which is of great significance for the development of new drugs and therapeutic strategies. In addition, it is also of great value for understanding the pathogenesis and prevention of diseases.

How is FCER1A related to other genes or proteins? 08/20/2021

FCER1A has complex associations with other genes and proteins, such as its interaction with T cell receptors, inflammatory factors, etc.

Customer Reviews (3)

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Reviews
11/30/2022

    FCER1A can maintain its biological activity and structural integrity under specific experimental conditions.

    11/08/2022

      FCER1A quality is stable and reliable, with no significant differences between batches.

      01/15/2021

        FCER1A has high chemical and physical stability and is suitable for long-term storage and use.

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