FEZ1
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Official Full Name
fasciculation and elongation protein zeta 1 (zygin I)
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Overview
Fasciculation and elongation protein zeta-1 is a protein that in humans is encoded by the FEZ1 gene.This gene is an ortholog of the C. elegans unc-76 gene, which is necessary for normal axonal bundling and elongation within axon bundles. Expression of this gene in C. elegans unc-76 mutants can restore to the mutants partial locomotion and axonal fasciculation, suggesting that it also functions in axonal outgrowth. The N-terminal half of the gene product is highly acidic. Alternatively spliced transcript variants encoding different isoforms of this protein have been described. -
Synonyms
Fasciculation and elongation protein zeta 1; Fasciculation and elongation protein zeta-1; Fez 1; Fez; Fez-like zinc finger protein; FEZ1; Fezl; Forebrain embryonic zinc-finger like protein; Zpf312; Zygin 1; Zygin-1; ZyginI;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- Rhesus Macaque
- Zebrafish
- E.coli
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- N/A
- N
- Involved Pathway
- Protein Function
- Interacting Protein
FEZ1 involved in several pathways and played different roles in them. We selected most pathways FEZ1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with FEZ1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
FEZ1 has several biochemical functions, for example, gamma-tubulin binding, protein N-terminus binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FEZ1 itself. We selected most functions FEZ1 had, and list some proteins which have the same functions with FEZ1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| gamma-tubulin binding | RAD51L3;LYN;CEP57;PIFO;SPATC1;DIXDC1;FEZ1;NDN;BLOC1S2A |
| protein N-terminus binding | SLC6A3;PEX19;SNF8;DCTN4;EXOC4;EIF3E;RND2;HAX1;FEZ1 |
| protein binding | ECT2;CYP4F2;TRIM3;AKAP9;RPS6KA5;RRM1;LMO3;CDC25B;SNAP23 |
| protein kinase C binding | ADAM9;PARD6A;DACT1;AVPR1A;SDPR;PARD3;DSP;HDAC7;GRK5 |
FEZ1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FEZ1 here. Most of them are supplied by our site. Hope this information will be useful for your research of FEZ1.
HTT; TTR; PAM16; TXNDC9; NEK1; CEP126; ULK1; MDM2; TAF9; oks16_human; HTATSF1
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