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FGFBP1

  • Official Full Name

    fibroblast growth factor binding protein 1

  • Overview

    This gene encodes a secreted fibroblast growth factor carrier protein. The encoded protein plays a critical role in cell proliferation, differentiation and migration by binding to fibroblast growth factors and potentiating their biological effects on target cells. The encoded protein may also play a role in tumor growth as an angiogenic switch molecule, and expression of this gene has been associated with several types of cancer including pancreatic and colorectal adenocarcinoma. A pseudogene of this gene is also located on the short arm of chromosome 4.
  • Synonyms

    FGFBP1; fibroblast growth factor binding protein 1; fibroblast growth factor-binding protein 1; FGFBP; HBP17; 17 kDa heparin binding growth factor binding protein; FGF binding protein 1; FGF BP; FGF BP1; Fibroblast growth factor binding protein 1 precursor; FGF-binding protein 1; 17 kDa HBGF-binding protein; heparin-binding growth factor binding protein; 17 kDa heparin-binding growth factor-binding protein; FGF-BP; FGF-BP1; FGFBP-1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Rat
  • Rhesus Macaque
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
  • T7|His
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human FGFBP1-548H Active Recombinant Human Fibroblast Growth Factor Binding Protein 1, His-tagged Mammalian cells His
Human FGFBP1-53H Recombinant Human FGFBP1 protein, T7/His-tagged E.coli T7/His
Human FGFBP1-6233HCL Recombinant Human FGFBP1 293 Cell Lysate HEK293 N/A
Human FGFBP1-4840HF Recombinant Full Length Human FGFBP1 Protein, GST-tagged In Vitro Cell Free System GST 234 amino acids
Human FGFBP1-4118H Recombinant Human FGFBP1 Protein, GST-tagged Wheat Germ GST
Human FGFBP1-2947H-B Recombinant Human FGFBP1 Protein Pre-coupled Magnetic Beads HEK293
Human FGFBP1-2947H Recombinant Human FGFBP1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat FGFBP1-2337R Recombinant Rat FGFBP1 Protein Mammalian Cell His
Rat FGFBP1-1994R-B Recombinant Rat FGFBP1 Protein Pre-coupled Magnetic Beads HEK293
Rat FGFBP1-1994R Recombinant Rat FGFBP1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque FGFBP1-1702R Recombinant Rhesus monkey FGFBP1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque FGFBP1-1524R-B Recombinant Rhesus Macaque FGFBP1 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque FGFBP1-1524R Recombinant Rhesus Macaque FGFBP1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • FGFBP1 Related Research Area

FGFBP1 involved in several pathways and played different roles in them. We selected most pathways FGFBP1 participated on our site, such as FGFR2 ligand binding and activation, FGFR2b ligand binding and activation, Signal Transduction, which may be useful for your reference. Also, other proteins which involved in the same pathway with FGFBP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
FGFR2 ligand binding and activationFGFBP1;FGFBP2;FGFBP3
FGFR2b ligand binding and activationFGFBP2;FGFBP3;FGFBP1
Signal TransductionTAX1BP1;FGFBP2;CIT;RXFP2B;GPR31B;AKR1C6;RGS12;RAMP1;FGFBP3
Signaling by FGFRFGFBP3;KAL1A;FGFBP1;KAL1;FGFBP2
Signaling by FGFR2FGFBP2;FGFBP1;FGFBP3

FGFBP1 has several biochemical functions, for example, fibroblast growth factor binding, heparin binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FGFBP1 itself. We selected most functions FGFBP1 had, and list some proteins which have the same functions with FGFBP1. You can find most of the proteins on our site.

Function Related Protein
fibroblast growth factor bindingHSPA9;TGFBR3;SCN5A;GLG1;FGFR1A;FGFR3;RPS2;FGFBP1;FGFR2
heparin bindingVEGFAA;WISP2;RSPO4;LIPH;PF4V1;F11;CXCL11;COL13A1;CTGFA
protein bindingVASP;NSFL1C;LYSMD1;pab1;MYBPC2;BRD2;PPP2R5B;EIF4H;KIF22

FGFBP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FGFBP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of FGFBP1.

FGF2; UBQLN4; ssrna_ug

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