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FOSB

  • Official Full Name

    FBJ murine osteosarcoma viral oncogene homolog B

  • Overview

    The Fos family of nuclear oncogenes includes c-Fos, FosB, Fos-related antigen 1 (FRA1), and Fos-related antigen 2 (FRA2). While most Fos proteins exist as a single isoform, the FosB protein exists as two isoforms: full-length FosB and a shorter form, FosB
  • Synonyms

    FOSB; FBJ murine osteosarcoma viral oncogene homolog B; protein fosB; activator protein 1; AP 1; DKFZp686C0818; GOS3; GOSB; G0S3; MGC42291; oncogene FOS B; G0/G1 switch regulatory protein 3; AP-1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Human
  • Zebrafish
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human FOSB-12964H Recombinant Human FOSB, GST-tagged E.coli GST 2-14a.a.
Human FOSB-1230H Recombinant Human FBJ Murine Osteosarcoma Viral Oncogene Homolog B E.coli N/A
Human FOSB-1303H Recombinant HumanFOSB,GST-tagged,113-151aa E.coli GST
Human FOSB-28107TH Recombinant Human FOSB E.coli N/A
Human FOSB-6167HCL Recombinant Human FOSB 293 Cell Lysate HEK293 N/A
Human FOSB-4425H Recombinant Human FOSB Protein, GST-tagged Wheat Germ GST
Human FOSB-01H Recombinant Human FOSB Protein, His-tagged E.coli His
Human FOSB-5040HF Recombinant Full Length Human FOSB Protein, GST-tagged In Vitro Cell Free System GST 289 amino acids
Zebrafish FOSB-1704Z Recombinant Zebrafish FOSB Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • FOSB Related Articles
  • FOSB Related Research Area

FOSB involved in several pathways and played different roles in them. We selected most pathways FOSB participated on our site, such as Osteoclast differentiation, Cocaine addiction, Alcoholism, which may be useful for your reference. Also, other proteins which involved in the same pathway with FOSB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Osteoclast differentiationCYBB;NCF2;TNFRSF11A;NFATC1;FYN;PPP3CB;FCGR4;FCGR2A;NOX1
Cocaine addictionGNAI3;GNAS;CREB3L3;GRM2;NFKB1;CREB3L2;GRIN3A;ATF6B;MAOA
AlcoholismMAP2K1;HIST2H4;HIST2H2BE;HIST2H4A;TH;GM14476;HIST1H3C;HIST1H4B;ARAF

FOSB has several biochemical functions, for example, DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding, transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FOSB itself. We selected most functions FOSB had, and list some proteins which have the same functions with FOSB. You can find most of the proteins on our site.

Function Related Protein
DNA bindingPHC2;ZFP35;SPATA24;SP140L;ZFP668;PIAS2;HIST1H3H;H2BFWT;SRY
RNA polymerase II core promoter proximal region sequence-specific DNA bindingGMEB1;MXD1;E2F4;ZFP639;KLF16;AKNA;CEBPE;PRDM1;NR5A2
transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific bindingATF3;RBPJA;SFPI1;ARNTL;FOSL1A;ARNTL2;SREBF1;FOS;MSX1
transcription factor bindingMED12;NKX3;ESR1;SMARCA4;FOXO4;PPARG;HEY2;DOT1L;TRP53
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific bindingESRRA;CEBPG;NR3C1;MESP1;RAX;SMAD4;TRP63;GLI2;TP53

FOSB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FOSB here. Most of them are supplied by our site. Hope this information will be useful for your research of FOSB.

hflC

Desai, BN; Harris, RBS; et al. Leptin in the hindbrain facilitates phosphorylation of STAT3 in the hypothalamus. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM 308:E351-E361(2015).
Saxena, A; Little, JT; et al. Angiotensin II type 1a receptors in subfornical organ contribute towards chronic intermittent hypoxia-associated sustained increase in mean arterial pressure. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY 308:H435-H446(2015).
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