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FOSL2

  • Official Full Name

    FOS-like antigen 2

  • Overview

    FRA-2 has homologous sequence with c-Fos, FRA-1, and FOS B. It forms heterodimers with c-Jun that recognize specific DNA sequences, such as the binding site for transcription factor AP-1.
  • Synonyms

    FOSL2; FOS-like antigen 2; fos-related antigen 2; FLJ23306; FRA2; FRA-2;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • SUMO
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human FOSL2-799H Recombinant Human FOSL2 Protein, His-tagged E.coli His
Human FOSL2-6165HCL Recombinant Human FOSL2 293 Cell Lysate HEK293 N/A
Human FOSL2-4428H Recombinant Human FOSL2 Protein, GST-tagged Wheat Germ GST
Human FOSL2-2927H Recombinant Human FOSL2 protein, His-SUMO-tagged E.coli His-SUMO 1-326aa
Human FOSL2-5043HF Recombinant Full Length Human FOSL2 Protein, GST-tagged In Vitro Cell Free System GST 122 amino acids
Mouse FOSL2-5974M Recombinant Mouse FOSL2 Protein Mammalian Cell His
Mouse FOSL2-3312M-B Recombinant Mouse FOSL2 Protein Pre-coupled Magnetic Beads HEK293
Mouse FOSL2-3312M Recombinant Mouse FOSL2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque FOSL2-1739R Recombinant Rhesus monkey FOSL2 Protein, His-tagged Mammalian Cell His
Rhesus Macaque FOSL2-1561R-B Recombinant Rhesus Macaque FOSL2 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque FOSL2-1561R Recombinant Rhesus Macaque FOSL2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish FOSL2-5326Z Recombinant Zebrafish FOSL2 Mammalian Cell His
Chicken FOSL2-3495C Recombinant Chicken FOSL2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • FOSL2 Related Articles

FOSL2 involved in several pathways and played different roles in them. We selected most pathways FOSL2 participated on our site, such as Osteoclast differentiation, which may be useful for your reference. Also, other proteins which involved in the same pathway with FOSL2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Osteoclast differentiationNFKBIA;LCP2;TNFRSF1A;PIK3CB;FCGR4;NOX3;IFNGR1;TGFBR1;NFKB1

FOSL2 has several biochemical functions, for example, RNA polymerase II core promoter proximal region sequence-specific DNA binding, chromatin binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FOSL2 itself. We selected most functions FOSL2 had, and list some proteins which have the same functions with FOSL2. You can find most of the proteins on our site.

Function Related Protein
RNA polymerase II core promoter proximal region sequence-specific DNA bindingCUX2;SMAD2;NDN;PGR;JDP2;MXD1;NFIB;HNRNPK;MITFB
chromatin bindingKLF14;MAZ;SMARCD1;TRPS1;MSGN1;Ar;ARID5A;BAP1;SSRP1A
protein bindingLGR5;HTR3C;ALOX15;AHNAK;VPS16;SLIT2;DNAJA4;RAB4A;PPARA
transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific bindingARNTL;FOS;BATF2;CLOCK;FOSL1A;SREBF1;ARNTL2;RBPJB;IRF7
transcription factor activity, sequence-specific DNA bindingNEUROD1;HOXA5A;RARGA;RBPJL;HOXB5B;SALL2;POU3F3A;NFYA;ZNF146

FOSL2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FOSL2 here. Most of them are supplied by our site. Hope this information will be useful for your research of FOSL2.

JUN; JUNB; JUND; DDIT3; CREB5; TRAF1

Gast, H; Muller, A; et al. CD40 activation induces NREM sleep and modulates genes associated with sleep homeostasis. BRAIN BEHAVIOR AND IMMUNITY 27:133-144(2013).
Doucet, JP; Nakabeppu, Y; et al. Chronic alterations in dopaminergic neurotransmission produce a persistent elevation of Delta FosB-like protein(s) in both the rodent and primate striatum. EUROPEAN JOURNAL OF NEUROSCIENCE 8:365-381(1996).
SHARP, FR; SAGAR, SM; et al. C-FOS MESSENGER-RNA, FOS, AND FOS-RELATED ANTIGEN INDUCTION BY HYPERTONIC SALINE AND STRESS. JOURNAL OF NEUROSCIENCE 11:2321-2331(1991).
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