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FOXE1

Official Full Name

forkhead box E1 (thyroid transcription factor 2)
Overview

This intronless gene belongs to the forkhead family of transcription factors, which is characterized by a distinct forkhead domain. This gene functions as a thyroid transcription factor which likely plays a crucial role in thyroid morphogenesis. Mutations in this gene are associated with congenital hypothyroidism and cleft palate with thyroid dysgenesis. The map localization of this gene suggests it may also be a candidate gene for squamous cell epithelioma and hereditary sensory neuropathy type I. [provided by RefSeq, Jul 2008]
Synonyms

FOXE1; forkhead box E1 (thyroid transcription factor 2); TTF2; FOXE2; HFKH4; HFKL5; TITF2; TTF-2; FKHL15; forkhead box protein E1; forkhead box E2; forkhead box protein E2; HNF-3/fork head-like protein 5; thyroid transcription factor 2; forkhead-related protein FKHL15; forkhead, drosophila, homolog-like 15;

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse

Source

E.coli
HEK293
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
N

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	FOXE1-5059HF	Recombinant Full Length Human FOXE1 Protein, GST-tagged	In Vitro Cell Free System	GST	373 amino acids	Inquiry
Human	FOXE1-4447H	Recombinant Human FOXE1 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Mouse	FOXE1-5986M	Recombinant Mouse FOXE1 Protein	Mammalian Cell	His		Inquiry
Mouse	FOXE1-3321M	Recombinant Mouse FOXE1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	Foxe1-1516M	Recombinant Mouse Foxe1 Protein, His-tagged	E.coli	N-His	Asn127-Met371	Inquiry
Mouse	FOXE1-3321M-B	Recombinant Mouse FOXE1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry

Involved Pathway
Protein Function
Interacting Protein
FOXE1 Related Articles

FOXE1 involved in several pathways and played different roles in them. We selected most pathways FOXE1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with FOXE1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

FOXE1 has several biochemical functions, for example, DNA binding, RNA polymerase II transcription factor activity, sequence-specific DNA binding, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FOXE1 itself. We selected most functions FOXE1 had, and list some proteins which have the same functions with FOXE1. You can find most of the proteins on our site.

Function	Related Protein
DNA binding	AHRRB;ZNF280A;ZNF571;SCRT2;FOXF1;KCNIP3;SIX6A;ZNF354A;MEIOB
RNA polymerase II transcription factor activity, sequence-specific DNA binding	MED1;ZNF215;FOXL1;TFDP1B;ZNF131;GATA6;MEF2A;BETA3;TFDP1A
sequence-specific DNA binding	DBPA;ZFP13;CAMTA2;MAFK;ENG2B;BCL11AA;TSN;HOXD10A;HMX2
transcription factor activity, sequence-specific DNA binding	ZNF773;ETV5B;GTF2H2;PA2G4;MAFGB;MYT1;SOX4;ZNF286A;TULP4

FOXE1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FOXE1 here. Most of them are supplied by our site. Hope this information will be useful for your research of FOXE1.

Figlioli, G; Chen, BW; et al. Novel genetic variants in differentiated thyroid cancer and assessment of the cumulative risk. SCIENTIFIC REPORTS 5:-(2015).

Pereda, CM; Lesueur, F; et al. Common variants at the 9q22.33, 14q13.3 and ATM loci, and risk of differentiated thyroid cancer in the Cuban population. BMC GENETICS 16:-(2015).