FRG1
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Official Full Name
FSHD region gene 1
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Overview
This gene maps to a location 100 kb centromeric of the repeat units on chromosome 4q35 which are deleted in;facioscapulohumeral muscular dystrophy (FSHD). It is evolutionarily conserved and has related sequences on multiple;human chromosomes but DNA sequence analysis did not reveal any homology to known genes. In vivo studies demonstrate;the encoded protein is localized to the nucleolus. -
Synonyms
FRG1; FSHD region gene 1; protein FRG1; FRG1A; FSG1; FRG1_HUMAN; FSHD region gene 1 protein; OTTHUMP00000217759; facioscapulohumeral muscular dystrophy region gene-1;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rhesus Macaque
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- Myc|DDK
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
FRG1 involved in several pathways and played different roles in them. We selected most pathways FRG1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with FRG1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
FRG1 has several biochemical functions, for example, actin binding, poly(A) RNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FRG1 itself. We selected most functions FRG1 had, and list some proteins which have the same functions with FRG1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| actin binding | FGD4;TAGLN;DMD;CAPG;INPPL1;POF1B;LIMCH1;GC;PAWR |
| poly(A) RNA binding | C14orf166;AGO3;DHX29;SRSF10;RPS20;HIST1H4A;HUWE1;HMGN2;TRUB2 |
| protein binding | ZWINT;GLP1R;TROAP;NFS1;VARS2;CLC;FZD3;AHSA1;RWDD1 |
FRG1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FRG1 here. Most of them are supplied by our site. Hope this information will be useful for your research of FRG1.
KRT40; EXOSC8; LZTS2; CWC22; SART3; RBPMS; PTBP3
- Q&As
- Reviews
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