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FSCN2

  • Official Full Name

    fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus)

  • Overview

    This gene encodes a member of the fascin protein family. Fascins crosslink actin into filamentous bundles within dynamic cell extensions. This family member is proposed to play a role in photoreceptor disk morphogenesis. A mutation in this gene results in one form of autosomal dominant retinitis pigmentosa and macular degeneration. Multiple transcript variants encoding different isoforms have been found for this gene.
  • Synonyms

    FSCN2; fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus); fascin (Strongylocentrotus purpuratus) homolog 2 (actin bundling protein, retinal); fascin-2; RFSN; RP30; Fascin homolog 2, actin bundling protein, retinal Strongylocentrotus purpuratus; Fascin Strongylocentrotus purpuratus homolog 2 actin bundling protein, retinal; FSCN2_HUMAN; Retinal fascin;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human FSCN2-1278H Recombinant Human FSCN2 protein, His-tagged E.coli His Gln8~His258 (Accession # O14926)
Human FSCN2-852H Recombinant Human FSCN2 Mammalian Cell His
Human FSCN2-2977H-B Recombinant Human FSCN2 Protein Pre-coupled Magnetic Beads HEK293
Human FSCN2-4512H Recombinant Human FSCN2 Protein, GST-tagged Wheat Germ GST
Human FSCN2-5078HF Recombinant Full Length Human FSCN2 Protein, GST-tagged In Vitro Cell Free System GST 492 amino acids
Human FSCN2-2977H Recombinant Human FSCN2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human FSCN2-2682H Recombinant Human FSCN2 Protein (Gln8-His258), His tagged E.coli His Gln8-His258
Mouse FSCN2-6055M Recombinant Mouse FSCN2 Protein Mammalian Cell His
Mouse Fscn2-1279M Recombinant Mouse Fscn2 protein, His-tagged E.coli His Gln8~Asn278 (Accession # Q32M02)
Mouse FSCN2-3371M Recombinant Mouse FSCN2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse FSCN2-3371M-B Recombinant Mouse FSCN2 Protein Pre-coupled Magnetic Beads HEK293
Chicken FSCN2-4091C Recombinant Chicken FSCN2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • FSCN2 Related Articles
  • FSCN2 Related Research Area

FSCN2 involved in several pathways and played different roles in them. We selected most pathways FSCN2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with FSCN2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

FSCN2 has several biochemical functions, for example, actin binding, actin filament binding, protein binding, bridging. Some of the functions are cooperated with other proteins, some of the functions could acted by FSCN2 itself. We selected most functions FSCN2 had, and list some proteins which have the same functions with FSCN2. You can find most of the proteins on our site.

Function Related Protein
actin bindingMTSS1LA;SVILA;CAMK2B;FLNC;MKL1B;PHACTR3A;ALDOA;SYNE1;PTK2
actin filament bindingRCSD1;ADD2;GAS7;SMYHC2;PPP1R9A;FLNC;EGFR;CTNNA3;SYNE3
protein binding, bridgingFSCN1A;TRIM22;WWC1;COL1A2;NUFIP1;PPP4R2;SPRR1B;NMD3;FGG

FSCN2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FSCN2 here. Most of them are supplied by our site. Hope this information will be useful for your research of FSCN2.

Soundararajan, R; Won, J; et al. Gene Profiling of Postnatal Mfrp(rd6) Mutant Eyes Reveals Differential Accumulation of Prss56, Visual Cycle and Phototransduction mRNAs. PLOS ONE 9:-(2014).
Ohmen, J; Kang, EY; et al. Genome-Wide Association Study for Age-Related Hearing Loss (AHL) in the Mouse: A Meta-Analysis. JARO-JOURNAL OF THE ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGY 15:335-352(2014).
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