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FURIN

  • Official Full Name

    furin (paired basic amino acid cleaving enzyme)

  • Overview

    Proteins are normally synthesized in an inactive form and later require proteolytic processing to become active. Proprotein convertases make up a family of serine proteases capable of activating substrates that will subsequently intervene in extracellular
  • Synonyms

    FURIN; furin (paired basic amino acid cleaving enzyme); FUR, PACE, paired basic amino acid cleaving enzyme (furin, membrane associated receptor protein) , PCSK3; SPC1; FES upstream region; dibasic processing enzyme; dibasic-processing enzyme; furi;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Bos taurus (Bovine)
  • Chicken
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Rat
  • Rattus norvegicus (Rat)
  • Rhesus Macaque
  • Xenopus laevis (African clawed frog)
  • BSC40
  • CHO
  • Drosophila melanogaster Schneider 2 cells
  • E.coli
  • E.coli expression system
  • HEK293
  • HEK293T
  • Hi-5 Insect Cell
  • In Vitro Cell Free System
  • Insect Cell
  • Mammalian Cell
  • Mammalian cells
  • Sf9 Insect Cell
  • Wheat Germ
  • C
  • GFP
  • His
  • Flag
  • GST
  • His (Fc)
  • Avi
  • His|GST
  • Myc
  • DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human FURIN-16H Active Recombinant Human FURIN protein, His-tagged Mammalian cells His
Human FURIN-755H Recombinant Human Furin (Paired Basic Amino Acid Cleaving Enzyme) BSC40 N/A
Human FURIN-606H Recombinant Human FURIN, His-tagged Hi-5 Insect Cell His
Human FURIN-17H Recombinant Human FURIN protein, His-tagged HEK293 His Asp108-Glu715
Human FURIN-7820H Recombinant Human FURIN protein, His & GST-tagged E.coli His/GST Cys587~Lys748 (Accession # P09958)
Human FURIN-13036H Recombinant Human FURIN, His-tagged E.coli His C-term-300a.a.
Human FURIN-605H Active Recombinant Human FURIN Protein Drosophila melanogaster Schneider 2 cells N/A
Human FURIN-720H Recombinant Human Furin (Paired Basic Amino Acid Cleaving Enzyme) Sf9 Insect Cell N/A
Human FURIN-6119HCL Recombinant Human FURIN 293 Cell Lysate HEK293 N/A
Human FURIN-4553H Active Recombinant Human FURIN Protein Insect Cell N/A
Human FURIN-130H Recombinant Human FURIN protein, His-tagged E.coli His Thr105~Ile221
Human FURIN-4554H Recombinant Human FURIN Protein, GST-tagged Wheat Germ GST
Human FURIN-5158HF Recombinant Full Length Human FURIN Protein, GST-tagged In Vitro Cell Free System GST 28-794 amino acids
Human FURIN-6584H Recombinant Human FURIN Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human FURIN-946H Recombinant Human FURIN Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human FURIN-131H Recombinant Human FURIN protein, His-tagged E.coli His Asn385~Asp500
Human FURIN-861HFL Recombinant Full Length Human FURIN Protein, C-Flag-tagged Mammalian cells Flag
Human FURIN-30H Recombinant Human FURIN Protein (AA 27-715), C-GFP/His-Tagged HEK293 C-GFP/His AA 27-715
Human FURIN-3160H Recombinant Human FURIN Protein (Thr105-Ile221), N-His tagged E.coli N-His Thr105-Ile221
Human FURIN-946H-B Recombinant Human FURIN Protein Pre-coupled Magnetic Beads HEK293
Human FURIN-1468H Active Recombinant Human FURIN protein, His-tagged HEK293 His Gln27-Ala574
Mouse Furin-566M Active Recombinant Mouse Furin (paired basic amino acid cleaving enzyme) CHO His
Mouse FURIN-6087M Recombinant Mouse FURIN Protein Mammalian Cell His
Mouse Furin-7822M Recombinant Mouse Furin protein, His & GST-tagged E.coli His/GST Leu578~Phe734 (Accession # P23188)
Mouse Furin-7821M Recombinant Mouse Furin protein, His-tagged E.coli His Arg418~Thr573 (Accession # P23188)
Mouse Furin-3106M Recombinant Mouse Furin Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse FURIN-3390M Recombinant Mouse FURIN Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse FURIN-3390M-B Recombinant Mouse FURIN Protein Pre-coupled Magnetic Beads HEK293
Rat FURIN-2410R Recombinant Rat FURIN Protein Mammalian Cell His
Rat FURIN-2066R-B Recombinant Rat FURIN Protein Pre-coupled Magnetic Beads HEK293
Rat FURIN-2066R Recombinant Rat FURIN Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Bos taurus (Bovine) RFL22527BF Recombinant Full Length Bovine Furin(Furin) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (108-797)
Homo sapiens (Human) RFL17360HF Recombinant Full Length Human Furin(Furin) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (108-794)
Mus musculus (Mouse) RFL21837MF Recombinant Full Length Mouse Furin(Furin) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (108-793)
Rattus norvegicus (Rat) RFL14576RF Recombinant Full Length Rat Furin(Furin) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (108-793)
Rhesus Macaque FURIN-1767R Recombinant Rhesus monkey FURIN Protein, His-tagged Mammalian Cell His
Rhesus Macaque FURIN-1588R Recombinant Rhesus Macaque FURIN Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque FURIN-1588R-B Recombinant Rhesus Macaque FURIN Protein Pre-coupled Magnetic Beads HEK293
Xenopus laevis (African clawed frog) RFL12855XF Recombinant Full Length Xenopus Laevis Furin-1(Furin) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (106-783)
Chicken FURIN-6280C Recombinant Chicken FURIN Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • FURIN Related Articles
  • FURIN Related Signal Pathway

FURIN involved in several pathways and played different roles in them. We selected most pathways FURIN participated on our site, such as Influenza A, which may be useful for your reference. Also, other proteins which involved in the same pathway with FURIN were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Influenza ARAF1;CCL2;HLA-DQB1;KPNA1;TMPRSS4;MX1;IL33;EIF2AK1;PABPN1L

FURIN has several biochemical functions, for example, endopeptidase activity, metal ion binding, nerve growth factor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FURIN itself. We selected most functions FURIN had, and list some proteins which have the same functions with FURIN. You can find most of the proteins on our site.

Function Related Protein
endopeptidase activityFAP;PSMA4;TRAPPC12;ATG4B;ACE;RHBDD1;KLK1B1;PSMB5;HTRA4
metal ion bindingZFP1;ZNF684;CMTM2A;S100A10A;B4GALT4;ZNF785;TRIM35-20;EXO1;CAR3
nerve growth factor bindingNGFRB;SORT1;PCSK6;NTRK1;FURIN;NGFR
peptidase activityCAPN1A;TMPRSS4A;PARLA;PROCA;DCD;CASP3A;CAPN1B;OTUD4;OTUD5A
peptide bindingAVPR2;LTA4H;TPP1;CTSL2;ANPEP;AVPR2L;ERAP1;PPYR1;GNRHR1
protease bindingBRCA2;SELL;BCL2;TRIP4;FN1;SERPINB4;CCBE1;TP53;COMP
protein bindingSTOML2;MAPRE1;SLIRP;RAB11FIP2;USP46;EFEMP1;LHX4;GNB2;CD79B
serine-type endopeptidase activityKLK11;RHBDD3;PCSK1;KLK14;PCSK5B;CTSG;PLG;TMPRSS15;PRSS8
serine-type endopeptidase inhibitor activityEPPIN;SERPINH1;SERPINA10;SPINT4;SPINK10;GOPC;SPINT1A;SERPIND1;COL6A3

FURIN has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FURIN here. Most of them are supplied by our site. Hope this information will be useful for your research of FURIN.

MSTN; MST1R; DDX56; ABCC6; Gorasp2; BAG6; MMP14; HUWE1; Dennd6a; SGTB; TGOLN2; GORASP2; Spn42Da

Gierer, S; Muller, MA; et al. Inhibition of Proprotein Convertases Abrogates Processing of the Middle Eastern Respiratory Syndrome Coronavirus Spike Protein in Infected Cells but Does Not Reduce Viral Infectivity. JOURNAL OF INFECTIOUS DISEASES 211:889-897(2015).
Pasetto, M; Antignani, A; et al. Whole-genome RNAi screen highlights components of the endoplasmic reticulum/Golgi as a source of resistance to immunotoxin-mediated cytotoxicity. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 112:E1135-E1142(2015).
  • Q&As
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Customer Reviews (3)

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Reviews
10/10/2022

    The proteins purchased from your company are of very high quality and are suitable for WB experiments.

    02/04/2022

      High quality product at a good price, a satisfactory shopping experience.

      03/30/2021

        The staff were enthusiastic and proactive in communicating with me and solving many technical problems in a timely manner.

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