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FUT1

  • Official Full Name

    fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)

  • Overview

    The protein encoded by this gene is a Golgi stack membrane protein that is involved in the creation of a precursor of the H antigen, which is required for the final step in the soluble A and B antigen synthesis pathway. This gene is one of two encoding the galactoside 2-L-fucosyltransferase enzyme. Mutations in this gene are a cause of the H-Bombay blood group.
  • Synonyms

    FUT1; fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group); fucosyltransferase 1 (galactoside 2 alpha L fucosyltransferase) , fucosyltransferase 1 (galactoside 2 alpha L fucosyltransferase, Bombay phenotype included) , H, HSC; g;

  • Cell & Tissue Lysates
  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Rat
  • Rhesus Macaque
  • E.coli
  • E.coli expression system
  • HEK293
  • HEK293T
  • Human Cell
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
  • N
  • 6×His, GFP
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human FUT1-6117HCL Recombinant Human FUT1 293 Cell Lysate HEK293 N/A
Human FUT1-4558H Recombinant Human FUT1 Protein, His-tagged E.coli His
Human FUT1-1533H Recombinant Human FUT1 Protein, His-tagged E.coli N-His Trp149-Pro365
Human FUT1-4557H Recombinant Human FUT1 Protein, GST-tagged Wheat Germ GST
Human FUT1-5173HF Recombinant Full Length Human FUT1 Protein, GST-tagged In Vitro Cell Free System GST 365 amino acids
Human FUT1-4559H Recombinant Human FUT1 Protein, His-tagged Human Cell His
Human FUT1-24H Active Recombinant Human FUT1 Protein (AA 26-365), N-6×His/GFP tagged HEK293 N-6×His, GFP AA 26-365
Mouse Fut1-1534M Recombinant Mouse Fut1 Protein, His-tagged E.coli N-His Gly109-Val377
Mouse Fut1-3108M Recombinant Mouse Fut1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat FUT1-2411R Recombinant Rat FUT1 Protein Mammalian Cell His
Rat Fut1-1535R Recombinant Rat Fut1 Protein, His-tagged E.coli N-His Thr140-Ala376
Rat FUT1-2067R Recombinant Rat FUT1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat FUT1-2067R-B Recombinant Rat FUT1 Protein Pre-coupled Magnetic Beads HEK293
Homo sapiens (Human) RFL8415HF Recombinant Full Length Human Galactoside 2-Alpha-L-Fucosyltransferase 1(Fut1) Protein, His-Tagged E.coli expression system His Full Length (1-365)
Mus musculus (Mouse) RFL8881MF Recombinant Full Length Mouse Galactoside 2-Alpha-L-Fucosyltransferase 1(Fut1) Protein, His-Tagged E.coli expression system His Full Length (1-376)
Rhesus Macaque FUT1-1768R Recombinant Rhesus monkey FUT1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque FUT1-1589R Recombinant Rhesus Macaque FUT1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque FUT1-1589R-B Recombinant Rhesus Macaque FUT1 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • FUT1 Related Articles

FUT1 involved in several pathways and played different roles in them. We selected most pathways FUT1 participated on our site, such as Glycosphingolipid biosynthesis - lacto and neolacto series, Glycosphingolipid biosynthesis - globo series, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with FUT1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Glycosphingolipid biosynthesis - lacto and neolacto seriesB3GALT5;B3GNT3;ABO;ST3GAL6;B3GALT2;B4GALT4;FUT9;B3GNT2;FUT3
Glycosphingolipid biosynthesis - globo seriesFUT2;NAGA;HEXA;FUT9A;GBGT1L4;FUT9;A4GALT;ST8SIA1;B3GALNT1
Metabolic pathwaysMGAT2;PPCS;CDA;UPB1;B3GALT5;MRI1;BPGM;HK1;ITPKB

FUT1 has several biochemical functions, for example, fucosyltransferase activity, galactoside 2-alpha-L-fucosyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by FUT1 itself. We selected most functions FUT1 had, and list some proteins which have the same functions with FUT1. You can find most of the proteins on our site.

Function Related Protein
fucosyltransferase activityFUT9;B3GNT8;GALNT18A;PIGB;POFUT1;FUT9A;B3GNTL1;B3GNT9-PS;GALNTL4
galactoside 2-alpha-L-fucosyltransferase activityFUT1;FUT2

FUT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FUT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of FUT1.

Nonaka, M; Fukuda, MN; et al. Determination of Carbohydrate Structure Recognized by Prostate-specific F77 Monoclonal Antibody through Expression Analysis of Glycosyltransferase Genes. JOURNAL OF BIOLOGICAL CHEMISTRY 289:16478-16486(2014).
Aziz, F; Qiu, Y; et al. The Role of Anti-LeY Antibody in the Downregulation of MAPKs/COX-2 Pathway in Gastric Cancer. CURRENT DRUG TARGETS 15:469-476(2014).
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