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FUT2

  • Official Full Name

    fucosyltransferase 2 (secretor status included)

  • Overview

    The protein encoded by this gene is a Golgi stack membrane protein that is involved in the creation of a precursor of the H antigen, which is required for the final step in the soluble A and B antigen synthesis pathway. This gene is one of two encoding the galactoside 2-L-fucosyltransferase enzyme. Two transcript variants encoding the same protein have been found for this gene.
  • Synonyms

    FUT2; fucosyltransferase 2 (secretor status included); SE; galactoside 2-alpha-L-fucosyltransferase 2; alpha (1; 2) fucosyltransferase; alpha(1; 2)FT2; galactoside 2 alpha L fucosyltransferase 2; GDP L fucose:beta D galactoside 2 alpha L fucosyltransferase 2; Se2; SEC2; secretor blood group alpha 2 fucosyltransferase; secretor factor; sej; Fucosyltransferase 2; alpha(1,2)FT2; alpha(1,2)FT 2; OTTHUMP00000226681; OTTHUMP00000226682; alpha (1,2) fucosyltransferase; secretor blood group alpha-2-fucosyltransferase; GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosylt; B12QTL1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Gorilla gorilla gorilla (Western lowland gorilla)
  • Human
  • Pan troglodytes (Chimpanzee)
  • Pongo pygmaeus (Bornean orangutan)
  • Rat
  • E.coli
  • E.coli expression system
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • C
  • His
  • GST
  • His (Fc)
  • Avi
  • N/A
  • N
  • 6×His, GFP
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human FUT2-13H Recombinant Human FUT2 Protein, C-His-tagged HEK293 C-His Ile35-His343
Human FUT2-6115HCL Recombinant Human FUT2 293 Cell Lysate HEK293 N/A
Human FUT2-4559H Recombinant Human FUT2 Protein, GST-tagged Wheat Germ GST
Human FUT2-2434H Recombinant Human FUT2 Protein (Gln29-His343), His tagged E.coli His Gln29-His343
Human FUT2-5177HF Recombinant Full Length Human FUT2 Protein, GST-tagged In Vitro Cell Free System GST 153 amino acids
Human FUT2-1536H Recombinant Human FUT2 Protein, His-tagged E.coli N-His Gln29-His343
Human FUT2-26H Recombinant Human FUT2 Protein (AA 34-343), N-6×His/GFP tagged HEK293 N-6×His, GFP AA 34-343
Rat FUT2-2414R Recombinant Rat FUT2 Protein Mammalian Cell His
Rat FUT2-2070R Recombinant Rat FUT2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat FUT2-2070R-B Recombinant Rat FUT2 Protein Pre-coupled Magnetic Beads HEK293
Gorilla gorilla gorilla (Western lowland gorilla) RFL10119GF Recombinant Full Length Gorilla Gorilla Gorilla Galactoside 2-Alpha-L-Fucosyltransferase 2(Fut2) Protein, His-Tagged E.coli expression system His Full Length (1-343)
Pan troglodytes (Chimpanzee) RFL16690PF Recombinant Full Length Pan Troglodytes Galactoside 2-Alpha-L-Fucosyltransferase 2(Fut2) Protein, His-Tagged E.coli expression system His Full Length (1-343)
Pongo pygmaeus (Bornean orangutan) RFL7555PF Recombinant Full Length Pongo Pygmaeus Galactoside 2-Alpha-L-Fucosyltransferase 2(Fut2) Protein, His-Tagged E.coli expression system His Full Length (1-343)
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • FUT2 Related Articles

FUT2 involved in several pathways and played different roles in them. We selected most pathways FUT2 participated on our site, such as Glycosphingolipid biosynthesis - lacto and neolacto series, Glycosphingolipid biosynthesis - globo series, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with FUT2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Glycosphingolipid biosynthesis - lacto and neolacto seriesFUT6;B3GNTL2;ST3GAL3B;FUT5;B3GNT4;FUT1;B3GNT1;B3GNT5B;B3GNT2B
Glycosphingolipid biosynthesis - globo seriesFUT9A;A4GALT;FUT1;NAGA;GLA;ST8SIA1;GBGT1;ST3GAL2;HEXA
Metabolic pathwaysHIBADHB;SMPD2;INPP5L;PYGMA;B3GNT4;PLCB4;ATP6V0C;MTHFD1;UQCRB

FUT2 has several biochemical functions, for example, fucosyltransferase activity, galactoside 2-alpha-L-fucosyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by FUT2 itself. We selected most functions FUT2 had, and list some proteins which have the same functions with FUT2. You can find most of the proteins on our site.

Function Related Protein
fucosyltransferase activityFUT9B;POMGNT2;B3GNT9-PS;FUT1;PIGB;FUT7;UGGT1;FUT9A;FUT4
galactoside 2-alpha-L-fucosyltransferase activityFUT2;FUT1

FUT2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FUT2 here. Most of them are supplied by our site. Hope this information will be useful for your research of FUT2.

ZDHHC17

Friedrich, M; Diegelmann, J; et al. IL-17A Alone Weakly Affects the Transcriptome of Intestinal Epithelial Cells but Strongly Modulates the TNF-alpha-induced Expression of Inflammatory Mediators and Inflammatory Bowel Disease Susceptibility Genes. INFLAMMATORY BOWEL DISEASES 20:1502-1515(2014).
Khodayar-Pardo, P; Martinez-Costa, C; et al. Norovirus GII.4 Antibodies in Breast Milk and Serum Samples Their Role Preventing Virus-Like Particles Binding to Their Receptors. PEDIATRIC INFECTIOUS DISEASE JOURNAL 33:554-559(2014).
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