FXR1
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Official Full Name
fragile X mental retardation, autosomal homolog 1
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Overview
Fragile X mental retardation-related protein 1 (FXR1) and FXR2 are members of the FMR1 family sharing a very high degree of protein similarity among them. They interact with each other and also with FMR1, moving between the cytoplasm and the nucleus. FXR1 is an RNA binding protein and is expressed in the heart, kidney, brain, and testis. Mutations in FMR1 result in the most common form of mental retardation. -
Synonyms
FXR1; fragile X mental retardation, autosomal homolog 1; fragile X mental retardation syndrome-related protein 1; hFXR1p; FXR1P;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Rat
- Zebrafish
- E. coli
- E.coli
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- C
- His
- GST
- His (Fc)
- Avi
- N/A
- N
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
---|---|---|---|---|---|---|
Human | FXR1-13052H | Recombinant Human FXR1 protein, GST-tagged | E.coli | GST | 1-353 aa | |
Human | FXR1-941H | Recombinant Human FXR1 protein, GST-tagged | Wheat Germ | GST | ||
Human | FXR1-6106HCL | Recombinant Human FXR1 293 Cell Lysate | HEK293 | N/A | ||
Human | FXR1-13053H | Recombinant Human FXR1 protein, His-tagged | E.coli | His | 1-353 aa | |
Human | FXR1-587HF | Recombinant Full Length Human FXR1 Protein, GST-tagged | In Vitro Cell Free System | GST | 621 amino acids | |
Human | FXR1-2782H | Recombinant Human FXR1 protein(221-480 aa), C-His-tagged | E. coli | C-His | 221-480 aa | |
Mouse | FXR1-6101M | Recombinant Mouse FXR1 Protein | Mammalian Cell | His | ||
Mouse | FXR1-3399M-B | Recombinant Mouse FXR1 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Mouse | FXR1-3399M | Recombinant Mouse FXR1 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Rat | FXR1-2419R | Recombinant Rat FXR1 Protein | Mammalian Cell | His | ||
Rat | FXR1-2075R-B | Recombinant Rat FXR1 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Rat | FXR1-2075R | Recombinant Rat FXR1 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Rat | Fxr1-1538R | Recombinant Rat Fxr1 Protein, His&GST-tagged | E.coli | N-His&GST | Leu375-Asp568 | |
Zebrafish | FXR1-11449Z | Recombinant Zebrafish FXR1 | Mammalian Cell | His | ||
Chicken | FXR1-1971C | Recombinant Chicken FXR1 | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
- FXR1 Related Articles
FXR1 involved in several pathways and played different roles in them. We selected most pathways FXR1 participated on our site, such as RNA transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with FXR1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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RNA transport | EEF1A1B;CYFIP2;NUP210L;POM121L2;SIP1;UPF3B;EIF3HA;THOC4;NUP188 |
FXR1 has several biochemical functions, for example, G-quadruplex RNA binding, RNA binding, mRNA 3-UTR binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FXR1 itself. We selected most functions FXR1 had, and list some proteins which have the same functions with FXR1. You can find most of the proteins on our site.
Function | Related Protein |
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G-quadruplex RNA binding | Aff2;DHX36;FXR1;PATL2 |
RNA binding | NANOS3;SFPI1;DAZAP1;RPL5;SRSF1A;ZMAT4;CNOT7;CSDC2;IGF2BP2A |
mRNA 3-UTR binding | TARDBP;SECISBP2;RBMS3;LARP1;PUM1;RIMS2;YBX2;CPEB4;CSDA |
mRNA binding | RPL35;NUDT21;CLUHA;RPS26;C1QBP;RBPMS2B;CSTF2T;RBMX;RBFOX1 |
poly(A) RNA binding | MRPL1;HELZ2;YTHDF1;LSM4;EXOSC9;AKAP1;EIF2S1;RALYL;ZFP106 |
FXR1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FXR1 here. Most of them are supplied by our site. Hope this information will be useful for your research of FXR1.
CSNK2A1; PRSS23; HSPB1; GBP2; CRMP1; HABP4; q5nig6_fratt; RIF1; CYFIP2; CEP126; C14orf1; LUC7L2; UBA6; Max; ssrna_ug
- Q&As
- Reviews
Q&As (7)
Ask a questionTargeting FXR1 could offer therapeutic strategies for treating muscle disorders linked to RNA metabolism abnormalities.
FXR1, an RNA-binding protein, is involved in regulating RNA metabolism, particularly mRNA processing and turnover.
FXR1 interacts with a network of RNA-binding proteins, coordinating the regulation of mRNA metabolism.
FXR1 plays a crucial role in modulating protein synthesis by influencing mRNA availability and translation.
It contributes to mRNA stability, affecting the lifespan and translation efficiency of mRNAs.
Altered FXR1 activity can affect muscle development and function, potentially leading to muscle-related disorders.
Genetic mutations in FXR1 can disrupt normal RNA processing and protein synthesis, impacting various cellular functions.
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