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Fert2

Official Full Name

fer (fms/fps related) protein kinase, testis specific 2
Overview

FER is a member of the FPS/FES family of nontransmembrane receptor tyrosine kinases. FER plays a role in regulating cytoskeletal rearrangements and inside out signalling that accompany receptor ligand, cell matrix and cell cell interactions. Genetic analysis using transgenic mouse models implicate FER in the regulation of inflammation and innate immunity.
Synonyms

Fer; Flk; Flk_retired;

Species	Cat.#	Product name	Source (Host)	Tag	Price
Mouse	Fert2-310M	Recombinant Mouse Fert2, GST-tagged, Active	Sf9 Insect Cell	GST	Inquiry
Mouse	FERT2-5819M	Recombinant Mouse FERT2 Protein	Mammalian Cell	His	Inquiry
Mouse	FERT2-3211M	Recombinant Mouse FERT2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Mouse	FERT2-3211M-B	Recombinant Mouse FERT2 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry

Involved Pathway
Protein Function
Interacting Protein

Fert2 involved in several pathways and played different roles in them. We selected most pathways Fert2 participated on our site, such as Adherens junction, which may be useful for your reference. Also, other proteins which involved in the same pathway with Fert2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Adherens junction	EP300;ACTN3A;BAIAP2A;SMAD3;FYNB;RHOA;SNAI1;RHOAD;RAC1A

Fert2 has several biochemical functions, for example, ATP binding, Rab GTPase binding, actin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Fert2 itself. We selected most functions Fert2 had, and list some proteins which have the same functions with Fert2. You can find most of the proteins on our site.

Function	Related Protein
ATP binding	HSPA4L;EIF2AK1;SLFN5;POMK;DDX42;CNTN1B;MYH3;ABCG1;DHX38
Rab GTPase binding	RILP;RAB8A;MICAL1;ZFYVE20;STXBP5L;BICD1;ANKFY1;RAB11FIP4B;RABGGTA
actin binding	MSNA;SPIRE1;WASH1;MYO7B;MICAL2B;STRC;PLEC;EPB41L3B;WASL
cadherin binding	CD46;NDRG1;PSEN1;AKAP5;JUP;CDK5R1;CTNNA1;GNA13A;OLFM4
cell adhesion molecule binding	ADAM8;JUP;CADM1B;CADM1;CAML;PVRL1A;TENM2;PVRL2L;SELL
cytoskeletal protein binding	TNNT2A;EPB41B;MYLIP;EPB41L3B;FRMD3;ANXA2;EPB41L5;EPB41L3A;PTPN4
epidermal growth factor receptor binding	RNF126;FER;ARF4;HBEGF;HBEGFB;EREG;TNK2;EGF;CBLC
gamma-catenin binding	CTNNA1;FER;PTPRJ;Fert2;CDH2;DSG1A;PTPRK;APC;TCF7L2
kinase activity	EPHA4A;DCLK3;NLK1;TLK1B;PPM1E;CDK12;PRKAB1B;PRKD3;RAF1B
lipid binding	APODA.1;ALOX15B;FER;FABP1B.1;TRIP10A;FABP12;ACBD7;FNBP1;GPIHBP1
non-membrane spanning protein tyrosine kinase activity	PRKCD;FGR;PTK6;PTK6B;ZAP70;PTK2BB;FRK;RIPK2;BLK
nucleotide binding	MAP3K4;NLRP4C;BSK146;MAPK8B;TNIKB;ATP1A3A;MAP3K12;RBFOX3;ORC5
protein binding	EMILIN1;LAMTOR2;ANO2;MEF2C;CRLF3;GAS6;CENPW;HPS1;NTSR1
protein kinase activity	CDK7;MAP2K1;KITA;JAK2;CSNK1D;STK3;SLKA;RIPK1;DCLK2
protein kinase binding	SUFU;AURKA;HDAC7;KCNA5;SLC12A4;IKBKB;AGAP2;TRAF6;TPX2
protein phosphatase 1 binding	PPP1R11;PHACTR3A;STAU1;TCTEX1D4;PHACTR3B;LILRB2;PPP1R9B;PPP1R15A;PHACTR4B
protein tyrosine kinase activity	NTRK2B;PTK2;DYRK1B;AXL;EK1;IGF1RB;FGFR1;Fert2;FGFR2
receptor binding	ENSA;FGF20B;VTCN1;RSPO1;F2;NRG2A;Icosl;AKAP9;FGF8B
transferase activity	DCLK3;CSNK1DB;FUT8A;MGAT3A;EPHA4B;HS3ST1L2;PIP5K1AA;LASS5;UGT2B6

Fert2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Fert2 here. Most of them are supplied by our site. Hope this information will be useful for your research of Fert2.