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Fgd2

  • Official Full Name

    FYVE, RhoGEF and PH domain containing 2

  • Cell & Tissue Lysates
  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rhesus Macaque
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human FGD2-6254HCL Recombinant Human FGD2 293 Cell Lysate HEK293 N/A
Human FGD2-4786HF Recombinant Full Length Human FGD2 Protein, GST-tagged In Vitro Cell Free System GST 655 amino acids
Human FGD2-4089H Recombinant Human FGD2 Protein, GST-tagged Wheat Germ GST
Human FGD2-2709H Recombinant Human FGD2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Mouse FGD2-5832M Recombinant Mouse FGD2 Protein Mammalian Cell His
Mouse Fgd2-2991M Recombinant Mouse Fgd2 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse FGD2-3221M Recombinant Mouse FGD2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse FGD2-3221M-B Recombinant Mouse FGD2 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque FGD2-1691R Recombinant Rhesus monkey FGD2 Protein, His-tagged Mammalian Cell His
Rhesus Macaque FGD2-1513R-B Recombinant Rhesus Macaque FGD2 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque FGD2-1513R Recombinant Rhesus Macaque FGD2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Fgd2 Related Articles

Fgd2 involved in several pathways and played different roles in them. We selected most pathways Fgd2 participated on our site, such as Cell death signalling via NRAGE, NRIF and NADE, G alpha (12/13) signalling events, GPCR downstream signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with Fgd2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cell death signalling via NRAGE, NRIF and NADECASP2;BCL2L11;ARHGEF18A;AKAP13;ARHGAP4;ARHGEF9;FGD4A;ARHGEF16;ARHGEF18
G alpha (12/13) signalling eventsKALRN;ABR;RHOB;ARHGEF9;FGD4A;NET1;ARHGEF16;RHOGA;OBSCN
GPCR downstream signalingOPN1MW2;EDNRA;GPR132B;DGKB;OPN4;CHRM5;ANXA1A;CNR1;MCF2L
NRAGE signals death through JNKFGD2;AATF;FGD4;ECT2;OBSCN;ARHGAP4A;MCF2L;FGD4A;ARHGEF18
Rho GTPase cycleTAGAPA;TAGAP;ARHGAP22;ARHGAP11A;RHOF;ARHGAP23;ARHGAP24;RHOT2;ARHGEF18
Signal TransductionFMNL3;GUCA1E;WIPF2;RHOT1B;SCUBE2;CRHB;ARHGAP4A;APLN;RBP4
Signaling by GPCRPNOCB;INSL3;OPN4A;DCLRE1B;FGD2;OPN1SW1;GPR18;NMBA;NET1
Signaling by Rho GTPasesARHGAP11A;ARHGAP29;ARHGAP28;ARAP2;ARHGAP29B;RHOUA;PRC1;RHOV;NCKIPSD

Fgd2 has several biochemical functions, for example, Rho guanyl-nucleotide exchange factor activity, guanyl-nucleotide exchange factor activity, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Fgd2 itself. We selected most functions Fgd2 had, and list some proteins which have the same functions with Fgd2. You can find most of the proteins on our site.

Function Related Protein
Rho guanyl-nucleotide exchange factor activityITSN2;FGD1;VAV3;ARHGEF7B;ARHGEF7A;FARP1;PLEKHG6;FGD4;ARHGEF3
guanyl-nucleotide exchange factor activityRAPGEF3;SPATA13;ARHGEF37;GDPGP1;RAPGEFL1;FLCN;EIF2B5;RASGEF1BB;ARHGEF11
metal ion bindingZNF434;ZNF192;CASZ1;ZBTB33;ZNF10;ZNHIT3;TGFBR1;ZC3H8;GNA11
protein bindingKRTAP19-5;KAZN;RUSC1;RPS28;CCKBR;ZBED3;LAX1;MAPK1;TPRKB
small GTPase bindingFGD6;FGD3;FGD1;FGD2;GDI2;RCC2;ERRFI1;RNF152;FGD4

Fgd2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Fgd2 here. Most of them are supplied by our site. Hope this information will be useful for your research of Fgd2.

KLHL12; TMEM239; RNPS1

Cerda-Reverter, JM; Agulleiro, MJ; et al. Involvement of melanocortin receptor accessory proteins (MRAPs) in the function of melanocortin receptors. GENERAL AND COMPARATIVE ENDOCRINOLOGY 188:133-136(2013).
Hasler, R; Kerick, M; et al. Alterations of pre-mRNA splicing in human inflammatory bowel disease. EUROPEAN JOURNAL OF CELL BIOLOGY 90:603-611(2011).
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