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FGL2

  • Official Full Name

    fibrinogen-like 2

  • Overview

    The protein encoded by this gene is a secreted protein that is similar to the beta- and gamma-chains of fibrinogen. The carboxyl-terminus of the encoded protein consists of the fibrinogen-related domains (FRED). The encoded protein forms a tetrameric complex which is stabilized by interchain disulfide bonds. This protein may play a role in physiologic functions at mucosal sites.
  • Synonyms

    FGL2; fibrinogen-like 2; fibroleukin; pT49; T49; fibrinogen-like protein 2;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • CHO
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Yeast
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human FGL2-12886H Recombinant Human FGL2, GST-tagged E.coli GST 1-148a.a.
Human FGL2-12885H Recombinant Human FGL2 protein, His-tagged E.coli His Asn24~Pro439
Human FGL2-749H Recombinant Human FGL2 Mammalian Cell His
Human FGL2-187H Recombinant Human SFGL2 protein, MYC/DDK-tagged HEK293 Myc/DDK
Human FGL2-622HCL Recombinant Human FGL2 cell lysate N/A
Human FGL2-01H Active Recombinant Human FGL2 Protein, His-tagged CHO His
Human FGL2-4153H Recombinant Human FGL2 Protein, GST-tagged Wheat Germ GST
Human FGL2-3445H Recombinant Human FGL2 Protein (Ile209-Pro439), N-His tagged E.coli N-His Ile209-Pro439
Human FGL2-4944HF Recombinant Full Length Human FGL2 Protein, GST-tagged In Vitro Cell Free System GST 439 amino acids
Human FGL2-2949H Recombinant Human FGL2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human FGL2-2949H-B Recombinant Human FGL2 Protein Pre-coupled Magnetic Beads HEK293
Human FGL2-298HFL Recombinant Full Length Human FGL2 Protein, C-Flag-tagged Mammalian cells Flag
Human FGL2-1463H Recombinant Human FGL2 protein, His-tagged HEK293 His Pro204-Pro439
Human FGL2-1656H Recombinant Human FGL2 Protein (24-439 aa), His-tagged Yeast His 24-439 aa
Human FGL2-1464H Recombinant Human FGL2 protein, His-tagged HEK293 His Asn24-Pro439
Mouse FGL2-5869M Recombinant Mouse FGL2 Protein Mammalian Cell His
Mouse Fgl2-2715M Recombinant Mouse Fgl2 protein, His-tagged E.coli His Val20~Pro432
Mouse Fgl2-001M Active Recombinant Mouse Fgl2 Protein, His-tagged CHO His
Mouse Fgl2-3007M Recombinant Mouse Fgl2 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse Fgl2-4251M Recombinant Mouse Fgl2 protein, His-tagged E.coli His 20-432aa
Mouse FGL2-3245M Recombinant Mouse FGL2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse FGL2-3245M-B Recombinant Mouse FGL2 Protein Pre-coupled Magnetic Beads HEK293
Rat Fgl2-2716R Recombinant Rat Fgl2 protein, His-tagged E.coli His Phe263~Ser424 (Accession # Q32Q89)
Rhesus Macaque FGL2-1706R Recombinant Rhesus monkey FGL2 Protein, His-tagged Mammalian Cell His
Rhesus Macaque FGL2-1528R Recombinant Rhesus Macaque FGL2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque FGL2-1528R-B Recombinant Rhesus Macaque FGL2 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish FGL2-3153Z Recombinant Zebrafish FGL2 Mammalian Cell His
Chicken FGL2-3525C Recombinant Chicken FGL2 Mammalian Cell His
  • FGL2 Related Articles
  • FGL2 Related Research Area

FGL2 involved in several pathways and played different roles in them. We selected most pathways FGL2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with FGL2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

FGL2 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by FGL2 itself. We selected most functions FGL2 had, and list some proteins which have the same functions with FGL2. You can find most of the proteins on our site.

Function Related Protein

FGL2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FGL2 here. Most of them are supplied by our site. Hope this information will be useful for your research of FGL2.

Urbanellis, P; Shyu, W; et al. The regulatory T cell effector molecule fibrinogen-like protein 2 is necessary for the development of rapamycin-induced tolerance to fully MHC-mismatched murine cardiac allografts. IMMUNOLOGY 144:91-106(2015).
Sun, Y; Xi, D; et al. Soluble FGL2, a novel effector molecule of activated hepatic stellate cells, regulates T-cell function in cirrhotic patients with hepatocellular carcinoma. HEPATOLOGY INTERNATIONAL 8:567-575(2014).
  • Q&As
  • Reviews

Q&As (5)

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Is FGL2 protein a potential therapeutic target for autoimmune diseases? 08/26/2021

Yes, targeting FGL2 protein has shown promise in preclinical studies as a potential therapeutic strategy for autoimmune diseases.

How does FGL2 protein contribute to liver diseases? 07/23/2021

FGL2 protein has been implicated in liver fibrosis, cirrhosis, and hepatocellular carcinoma by promoting inflammation, fibrogenesis, and immune dysregulation.

What are the potential side effects of targeting FGL2 protein for therapy? 12/09/2020

Potential side effects may include immunosuppression, increased risk of infections, and dysregulation of immune homeostasis.

What are the current methods for detecting FGL2 protein in clinical samples? 12/01/2018

Enzyme-linked immunosorbent assay (ELISA) and immunohistochemistry are commonly used methods for detecting FGL2 protein in clinical samples.

How is FGL2 protein involved in cancer progression? 09/20/2017

FGL2 protein has been shown to promote cancer cell growth, invasion, and metastasis by modulating immune responses and promoting angiogenesis.

Customer Reviews (3)

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Reviews
11/17/2022

    By utilizing the FGL2 protein, I can approach my research with unwavering confidence in its quality, along with the unparalleled support provided by its manufacturer.

    04/13/2021

      Their expertise and prompt responsiveness exemplify their dedication to providing customers with solutions and guidance.

      08/16/2020

        The FGL2 protein offers exceptional quality that seamlessly aligns with my experimental requirements.

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