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GAL3ST1

  • Official Full Name

    galactose-3-O-sulfotransferase 1

  • Overview

    Sulfonation, an important step in the metabolism of many drugs, xenobiotics, hormones, and neurotransmitters, is catalyzed by sulfotransferases. The product of this gene is galactosylceramide sulfotransferase which catalyzes the conversion between 3-phosphoadenylylsulfate + a galactosylceramide to adenosine 3,5-bisphosphate + galactosylceramide sulfate. Activity of this sulfotransferase is enhanced in renal cell carcinoma.
  • Synonyms

    GAL3ST1; galactose-3-O-sulfotransferase 1; galactosylceramide sulfotransferase; cerebroside (3 phosphoadenylylsulfate:galactosylceramide 3) sulfotransferase; CST; 3 phosphoadenosine 5 phosphosulfate:GalCer sulfotransferase; 3 phosphoadenylylsulfate:galactosylceramide 3 sulfotransferase; Cerebroside sulfotransferase; Galactose 3 O sulfotransferase 1; GalCer sulfotransferase; 3-phosphoadenosine-5-phosphosulfate:GalCer sulfotransferase; 3-phosphoadenylylsulfate:galactosylceramide 3-sulfotransferase; cerebroside (3-phosphoadenylylsulfate:galactosylceramide 3) sulfotransferase;

  • Cell & Tissue Lysates
  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Rat
  • Rhesus Macaque
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • His|GST
  • His|T7
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human GAL3ST1-6046HCL Recombinant Human GAL3ST1 293 Cell Lysate HEK293 N/A
Human GAL3ST1-3307H Recombinant Human GAL3ST1 Protein (Leu57-Phe196), N-GST tagged E.coli N-GST Leu57-Phe196
Human GAL3ST1-1615H Recombinant Human GAL3ST1 protein, His & GST-tagged E.coli His/GST Leu57~Phe196 (Accession # Q99999)
Human GAL3ST1-4672H Recombinant Human GAL3ST1 Protein, GST-tagged Wheat Germ GST
Human GAL3ST1-5219HF Recombinant Full Length Human GAL3ST1 Protein, GST-tagged In Vitro Cell Free System GST 423 amino acids
Rat Gal3st1-1616R Recombinant Rat Gal3st1 protein, His & T7-tagged E.coli His/T7 Arg215~Trp423 (Accession # Q5PQK7)
Rhesus Macaque GAL3ST1-1801R Recombinant Rhesus monkey GAL3ST1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque GAL3ST1-1622R-B Recombinant Rhesus Macaque GAL3ST1 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque GAL3ST1-1622R Recombinant Rhesus Macaque GAL3ST1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • GAL3ST1 Related Articles

GAL3ST1 involved in several pathways and played different roles in them. We selected most pathways GAL3ST1 participated on our site, such as Ether lipid metabolism, Sphingolipid metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with GAL3ST1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Ether lipid metabolismPLA2G1B;PLA2G16;PLA2G5;PLB1;PLA2G4D;PAFAH2;PLA2G2A;PLA2G2D;UGT8
Sphingolipid metabolismSPTLC2A;SMPD1;SPTLC2;ARSF;ASAH1;SMPD2;CERS3B;NEU3.4;UGCG
Metabolic pathwaysACSS3;IPMK;PIGS;UROD;NT5C3L;SPTLC2A;NDUFS7;GCNT4A;mt-Atp8

GAL3ST1 has several biochemical functions, for example, galactosylceramide sulfotransferase activity, sulfotransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GAL3ST1 itself. We selected most functions GAL3ST1 had, and list some proteins which have the same functions with GAL3ST1. You can find most of the proteins on our site.

Function Related Protein
galactosylceramide sulfotransferase activityGAL3ST1;GAL3ST1A;GAL3ST4;GAL3ST3
sulfotransferase activitySULT1ST2;SULT5A1;HS3ST3B1A;Chst5;SULT1C2;SULT2ST2;SULT1ST8;SULT3ST4;SULT1ST3

GAL3ST1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GAL3ST1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GAL3ST1.

Hering, DM; Olenski, K; et al. Genome-Wide Association Study for Sperm Concentration in Holstein-Friesian Bulls. REPRODUCTION IN DOMESTIC ANIMALS 49:1008-1014(2014).
Goetstouwers, T; Van Poucke, M; et al. Variation in 12 porcine genes involved in the carbohydrate moiety assembly of glycosphingolipids does not account for differential binding of F4 Escherichia coli and their fimbriae. BMC GENETICS 15:-(2014).
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