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GALNT13

Official Full Name

UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13 (GalNAc-T13)
Overview

The GALNT13 protein is a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAcT; EC 2.4.1.41) family, which initiate O-linked glycosylation of mucins (see MUC3A, MIM 158371) by the initial transfer of N-acetylgalactosamine (GalNAc) with an alpha-linkage to a serine or threonine residue.
Synonyms

GALNT13; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13 (GalNAc-T13); polypeptide N-acetylgalactosaminyltransferase 13; GalNAc T13; KIAA1918; UDP N acetyl alpha D galactosamine:polypeptide N acetylgalactosaminyltransferase 13; GalNAc transferase 13; N acetylgalactosaminyltransferase 13; Polypeptide GalNAc transferase 13; pp GaNTase 13; Protein UDP acetylgalactosaminyltransferase 13; UDP GalNAc:polypeptide N acetylgalactosaminyltransferase 13; UDP N acetyl alpha D galactosamine:polypeptide; pp-GaNTase 13; protein-UDP acetylgalactosaminyltransferase 13; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 13; GalNAc-T13; H_NH0187G20.1; WUGSC:H_NH0187G20.1;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Rat

Source

HEK293
HEK293T
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
Myc
DDK
Myc|DDK
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	GALNT13-622H	Active Recombinant Human GALNT13 protein, His-tagged	HEK293	His		Inquiry
Human	GALNT13-623H	Recombinant Human GALNT13 protein, MYC/DDK-tagged	HEK293	Myc/DDK		Inquiry
Human	GALNT13-6038HCL	Recombinant Human GALNT13 293 Cell Lysate	HEK293	N/A		Inquiry
Human	GALNT13-4693H	Recombinant Human GALNT13 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	GALNT13-6166H	Recombinant Human GALNT13 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK		Inquiry
Human	GALNT13-5197HF	Recombinant Full Length Human GALNT13 Protein, GST-tagged	In Vitro Cell Free System	GST	556 amino acids	Inquiry
Mouse	Galnt13-3142M	Recombinant Mouse Galnt13 Protein, Myc/DDK-tagged	HEK293T	Myc/DDK		Inquiry
Rat	GALNT13-2467R	Recombinant Rat GALNT13 Protein	Mammalian Cell	His		Inquiry
Rat	GALNT13-2123R-B	Recombinant Rat GALNT13 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rat	GALNT13-2123R	Recombinant Rat GALNT13 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry

Involved Pathway
Protein Function
Interacting Protein
GALNT13 Related Articles

GALNT13 involved in several pathways and played different roles in them. We selected most pathways GALNT13 participated on our site, such as Metabolic pathways, Metabolism of proteins, Mucin type O-Glycan biosynthesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with GALNT13 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Metabolic pathways	CYP2P8;PLA2G12B;MTHFS;CYP27B1;B3GNT6;NDUFS3;CHIA.2;GATB;CYCS
Metabolism of proteins	CPB1;THSD7A;ADAMTS1;TOMM6;DMBT1;APEH;EXOC5;GRP;EEF1A1
Mucin type O-Glycan biosynthesis	WBSCR17;GALNT11;B4GALT5;C1GALT1B;GALNTL1;B3GNT6;POC1B-GALNT4;GALNT3;GALNT4
O-linked glycosylation	SPON1;ADAMTSL1;GALNT6;ADAMTS18;THSD1;ADAMTS1;ADAMTS13;ADAMTS4;KCNA6
O-linked glycosylation of mucins	MUC13;B3GNT8;MUC20;GALNT13;ST6GALNAC2;MUC5AC;MUC21;MUCL1;GALNT5
Post-translational protein modification	GALNTL5;NAPAA;ST8SIA3;PIGK;PHC3;DHPS;B3GNT6;TRAPPC6B;TMED2
mucin core 1 and core 2 O-glycosylation	GALNT5;GCNT3;GALNTL2;GALNT6;GALNT13

GALNT13 has several biochemical functions, for example, carbohydrate binding, metal ion binding, polypeptide N-acetylgalactosaminyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GALNT13 itself. We selected most functions GALNT13 had, and list some proteins which have the same functions with GALNT13. You can find most of the proteins on our site.

Function	Related Protein
carbohydrate binding	CLEC2H;PRG2;LGALS13;CD55;CLEC3A;HBL4;PYGB;SIGLEC6;NCAN
metal ion binding	DNAJA3A;EYA3;MSS51;SMAD6;TATDN3;ZNF621;BCL6A;ZNF438;PRICKLE2A
polypeptide N-acetylgalactosaminyltransferase activity	GALNT12;C1GALT1C1;GALNT1;GALNT9;GALNTL4;WBSCR17;GALNT5;GALNT13;GALNT6

GALNT13 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GALNT13 here. Most of them are supplied by our site. Hope this information will be useful for your research of GALNT13.

Dominguez, F; Moreno-Moya, JM; et al. Embryonic miRNA Profiles of Normal and Ectopic Pregnancies. PLOS ONE 9:-(2014).

Hussain, MRM; Nasir, J; et al. Clinically Significant Missense Variants in Human GALNT3, GALNT8, GALNT12, and GALNT13 Genes: Intriguing In Silico Findings. JOURNAL OF CELLULAR BIOCHEMISTRY 115:313-327(2014).